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Subject Index

A

A-Team, product placement in, 374

nicotine, 95 -96

via mouth, 78

acetaldehyde, filter for, 154

acetylcholine, nicotine effects on, 86

acidity

Food and Drug Administration, 94

nicotine

—absorption, 67 , 79 , 80

—delivery, 93 , 96

—extractable, 79

See also Extractable nicotine; Nicotine delivery

acrolein, filter for, 154

actron filter, 279 -280

ACVA Atlantic

CTR special project, 328

indoor air quality, 411 -412

See also Healthy Buildings International

Ad Hoc Committee, role in selecting special projects, 290

addiction

CTR not interested in studying, 304 -305

definition, 58

DSM III listing negative development for industry, 353

extent of nicotine addiction, 59

Food and Drug Administration, 102 , 103

habit, 80 , 81

necessary dose of nicotine, 84 , 102

nicotine, 15 , 68 , 69 , 74 , 80

Nicotine Addiction (Surgeon General's report). See Surgeon General's report, Nicotine Addiction

political problem, 249

procedures so companies could deny, 439

Sandefur, Thomas, comments, 105

selling nicotine, 58

Surgeon General's 1964 report, 100 -101

term, tobacco companies' reaction to, 305

tobacco companies, denials of nicotine addiction, 5

tolerance, 63 , 68

withdrawal, 64

See also Nicotine addiction; Smoker compensation

Addiction Research Foundation, CTR not interested, 304 -305

additives

allyl-isovalerate, 277

American position on disclosure of, 229

Ames test, 149 , 228 -229

anti-smoking groups' concerns, 228

benzyl acetate, 227

benzyl alcohol, 227

biological activity, effect on, 152 -153

biological activity, use of additives to reduce, 144

caffeine, 136 -137

carbon monoxide production, use of additives to affect, 19

Chemosol, 211

cinnamaldehyde, 227

cocoa, 220 -221

Committee of Council, 229

Comprehensive Smoking Education Act, 226

coumarin, 221 -223

D-Limonene, 227

destroying the data, 230

disclosure of, 225 -231

—pressure from Department of Health and Human Services, 229 -230

—pros and cons, 230 -231

eugenol, 211 , 227

extractable nicotine, use of additives to change, 81 , 83

filter characteristics, use of additives to change, 154

flavor and aroma of cigarette smoke, use of additives to change, 131

flavors, 149 , 202

food, additives in versus additives burned in tobacco, 202

glycerine (in Real cigarettes), 218

high-nicotine tobacco extract, 85

humectants, 211

independent industry panel on use of, 230 -231

inquiries, negative development for industry, 353

lawyers, 226 -228, 232 , 245

Liggett and Myers, position on disclosure of, 229

list of additives released by industry in 1994, 211 , 223 , 225 , 226 , 227 -228, 231

Lorillard, position on disclosure of, 229

menthol, 211

—in Real cigarettes, 218

mutagenicity of, 245

N-Bloctin, 147

nicotine delivery, use of additives to increase, 79

nicotine powder, 124

nothing artificial added, 218

PEI, 83

Philip Morris, position on disclosure of, 229

policy on testing of, 228 -229

polycyclic aromatic hydrocarbons, effect on, 144

potassium carbonate, 145

—use to reduce benzpyrene, 125

products liability, 230 , 232 , 233

public relations, 228 , 230 -231, 233

pure nicotine as an additive, avoiding, 85

pyridine, 227

pyrolysis, 201 , 204 , 211

R. J. Reynolds position on disclosure of, 229

regulatory aspects, 202 , 233

safrole (mace), 227

self-policing by industry, 230 -231

sidestream smoke, use of additives to reduce, 403 -404

sugar, 211

—in Real cigarettes, 218

titanium dioxide, 227

tobacco extract, 85

toxicity effected by pyrolysis of, 211

tumorgenic effects of, 19


513

types of, 202

use of, as undefendable, 231

vitamin A, 147

See also Additives Guidance Panel; and by specific additive

Additives Guidance Panel

changing role of, 232 -233

coumarin, 221 -222

diethylene glycol, 224

glycerol, 224

propylene glycol, 224

purpose of, 202 , 219

testing of additives by, excluding external testing, 232

admissibility in evidence, contract or in-house research on smoking and health, 275

advertising

brand advertising used to send political message, 191

Camel cigarettes, 28

countering health messages, 187 -193

editorial content, use of advertising dollars to influence, 357 , 358

First Amendment, 261 -262

health-image cigarettes, 26

healthier cigarettes, 28

Kent cigarettes, 29

Kool cigarettes, 28 , 29 , 387

less irritating cigarettes, 28

Lucky Strike cigarettes, 28

motion picture trailers, 287

nicotine delivery, 29

Old Gold cigarettes, 28

passive smoking and lung cancer, use of advertising to attack evidence on, 414

physician endorsements, 28

revenue losses threatened by anti-smoking legislation, 358

Viceroy cigarettes, 28 , 29

voluntary agreement between industry and Federal Trade Commission, 28

advertising restrictions

benefits to industry of broadcast advertising ban, 256 , 258

dealing with, 137 , 408

Federal Trade Commission, 260 -261

money lost by advertisers if advertising regulated, 358

product placement to circumvent television advertising restrictions, 365 , 368 -369

smokeless tobacco, efforts to prevent AMA from supporting, 312

Surgeon General's 1964 report, response to, 175

AFP. See Associated Film Promotion

agricultural chemical study group, 209

agriculture department. See Department of Agriculture

air pollution

CTR special report, 333

environmental tobacco smoke, 22 , 393 -394

See also Environmental tobacco smoke; Passive smoking; Sidestream smoke

ALEPH foundation, 321

All the Marbles, product placement in, 390

Allied Dunbar (UK), and BAT, 5

allyl-isovalerate, additives, 227

Alta Marea Productions, solicited product placement, 367

AMA-ERF. See American Medical Association; American Medical Association Education and Research Fund

AMC Theatres, Kool Jazz advertisements in, 387

American Brands

Addiction Research Foundation, 304

Council for Tobacco Research, 286

American Cancer Society

environmental tobacco smoke, 351

industry efforts to keep corporations from cooperating with, 355

nicotine-blocking agents, 99

Proposition 5 , 423 , 424

responding to, 73

"safe" cigarette research, 53

Surgeon General's 1964 report, anticipated response of, 51

threat to industry, 247

Tobacco Institute use of American Cancer Society study on passive smoking and lung cancer, 351 , 414

American Chemosol Corporation, 212 . See also Chemosol

American Heart Association

environmental tobacco smoke, 384

"safe" cigarette research by, 53

Surgeon General's 1964 report, anticipated reaction of, 51

American Legislative Exchange Council, Tobacco Institute contributions, 385

American Lung Association

Huber, Gary, presentation, 394

Sterling, Theodor, presentation, 297

American Medical Association

creating controversy about smoking and health, 181

Education and Research Fund report, as negative development for industry, 353

papers on Brown and Williamson documents, 11

public relations influenced by industry, 181 , 184

"safe" cigarette research, 53 , 128

Tiderock Corporation, 181 , 184

American Society of Heating, Refrigeration and Air-conditioning Engineers, presentation by Theodor Sterling, 299 -300

American Society of Legislative Clerks and Secretaries, Tobacco Institute support of, 385

American Tobacco Company

additives, position on disclosure of, 229

annual pesticide residue meeting, 209

Chemosol, 213

G-13 process to expand tobacco, 217

Tobacco Industry Research Committee, 33

workplace smoking, opposition to study of, 251

Ames test

additives, 149 , 228 -229

Additives Guidance Panel, 219

cigarette smoke, 228 -229, 302

definition, 148 , 229

lawyers, as avoiding Ames test studies, 303

league table, 20 , 148

mutagenicity of cigarettes, 20

ranking of cigarette brands, 20 , 148

sidestream smoke, 401

smoker compensation effects, 149 -150

ammonia, as affecting delivery of nicotine, 211

Amusement and Music Operators Association, Tobacco Institute support of, 386

analogues. See Nicotine analogues


514

anesthetic agent

eugenol, 211 , 219

menthol, 211

smoke easier to inhale, 219

annoyance, nonsmokers' reaction to environmental tobacco smoke, 334

annual pesticide residue meeting, 210

antifreeze, 223

anti-smoking groups, concern about additives, 228

antitrust issues

Chemosol, 285

Council for Tobacco Research, 285

fire-safe cigarette, 252 -253

laws, 284 -285

Microbiological Associates contract, 302

nicotine analogues, 286

aortic aneurysm, 19

Apocalypse Now, use of Marlboro cigarettes in, 372 -373

Ariel

Battelle Memorial Institute, 74 -77

cigarette design, 131

description, 74

Fate of Nicotine in the Body,74

idealized product, 104

less toxic cigarette, problems associated with marketing of, 440 -441

nicotine delivery device, use as, 62 , 65 , 82

patent, 75 -76

Philip Morris, 77

R. J. Reynolds, 77

"safe" cigarette research, 126

sharing information with research laboratories outside Britain, 82

status reports on, 78

arsenic

Borstal, 110

cigarette smoke, 31

asbestos

connection with smoking as negative development for tobacco industry, 353

Kent micronite filter, 29

ASHRAE. See American Society of Heating, Refrigeration and Air-conditioning Engineers

Associated Film Promotion (AFP)

audit of product placement expenses, 369 -371, 387 , 390

dissatisfaction with, 365

payment for product placements, 388 -389

product placement for Brown and Williamson, 365 -374

Sylvester Stallone, 365 -367, 370 , 371 , 373 , 389

termination of agreement with Brown and Williamson for product placements, 373 -374

See also Product placement

assumption of risk defense, in US versus UK, 340 -341

asthma, research relating to effects of environmental tobacco smoke on, 318

Atmospheric Health sciences, Domingo Aviado's consulting firm, 308

attorney-client privilege

avoidance of discovery, 241

Brown and Williamson documents, 236

definition, 236

fraud exception to, 238 -239

See also Work product rule

attorney work product. See Work product rule

attribution of statements of affiliated companies to Brown and Williamson, 6 , 267 , 273 -275

Avalon filter

description, 125

sharing information regarding, 71

Surgeon General's Advisory Committee, withholding information, 72 -73

avoidance of notes, memos, or lists, for deadwood documents, 235

avoiding disclosure of research results, 4

avoiding discovery. See Discovery

B

B, Project, 195 -197

"Bandwagons of Medicine," Henry Rothschild, 292 -293

BAP (BaP). See Benzo(a)pyrene

Barclay cigarettes

coumarin substitutes, 223

Federal Trade Commission smoking machines, 89

First Blood, product placement in, 371

Jinxed, product placement in, 371

product placement in movies, 368 -369

Tempest, dissatisfaction of Brown and Williamson with product placement in, 371

Barron's editorial, use of in Tobacco Institute advertisement, 175 -179

BAT

Allied Dunbar (UK), 5

Brown and Williamson, relationship to, 2 , 5 , 5 -6

cigarette brands, 2

Eagle Star (UK), 5

Farmers Group, 5

Imperial Tobacco (Canada), 5

insurance subsidiaries, 5

Batflake

biological activity, 165

carbon monoxide, 165

flue-cured tobacco, comparison with, 165

inhalation toxicology, 165

tobacco substitute, 164 -165

Battelle Memorial Institute

Ariel cigarette patents, 74 -77

Fate of Nicotine in the Body,15 , 65 -68

Hilton, Project, 153

Hippo I, Project, 62 -63

Hippo II, Project, 63 -65

Janus, Project, 125 , 143 -144

special account 4 research project at Columbus laboratory, 328

Surgeon General's Advisory Committee, withholding research from, 70 -73

"Tentative Hypothesis on Nicotine Addiction," 68 -70

Tobacco Industry Research Committee, 70

Tobacco Research Council, 70

workplace smoking study, 251

See also Fate of Nicotine in the Body ; Hippo I, Project; Hippo II, Project; Janus, Project

Batten, Barton, Durstine, and Osborne, backup advertisements for industry Proposition 5 campaign, 423

Belair cigarettes, use of advertising to communicate health and political information, 191

benefits

nicotine, 73

smoking, claims of benefits as legally dangerous, 344


515

Benson and Hedges

advertising to counter smoking restrictions, 188

Tobacco Industry Research Committee, 33

benzo(a)pyrene

carcinogen, 31 , 110

Chemosol, to reduce levels of, 212 , 213 -216

Microbiological Associates study of, 303

potassium carbonate, effect on, 126 -127

purer carcinogen, 215

"safe" cigarette research, 110 , 118

sidestream smoke, 402

benzyl acetate, additive, 227

benzyl alcohol, additive, 227

Beverly Hills Cop , Lucky Strike product placement in, 368

BIBRA (British Industry Biological Research Association), study of coumarin, 221 -222

biological activity

additives

—effect on, 152 -153

—use of to reduce, 144

Batflake, effect on, 165

blend, effect on, 152 -153

carcinogenicity, 21

design parameter for cigarettes, 131 , 138 , 139 -140, 154

environmental tobacco smoke, 152 -153

health-oriented cigarettes, 129 -130

legal issues, 269

low-delivery products, 142

minimizing, 129 , 20

sidestream smoke, 401 , 402 , 406

smoking behavior, effect on, 150

smoking machines versus human smoking, 150

substantially reduced, 139 -140

See also Carcinogenicity

biological effects, burning pesticides and additives, 204

biological research, dangerous, 167

biological tests

danger of demonstrating smoking causes cancer, 55

Hunter Commission, 164

sidestream smoke, avoiding, 245

sucker control agents, 204

Biological Research Meeting, glycoproteins, 396

Biological Testing Committee

B&W scientist attended, 133 , 278 , 281

sidestream smoke, 395

birth control pill warning, negative public relations development for industry, 353

Blackman report, rewriting of, 346 -352

bladder cancer

lawyers, as avoiding studies of, 303

Surgeon General's report, 18 , 19

Blue Skies Again , product placement in, 390

BOCA, presentation by Theodor Sterling, 300

body weight, effects of smoking on, 62 -63

Body & Soul , product placement in, 390

Body Heat , product placement in, 371 , 390

Borstal, arsenic, 110

boycotts, discouraging other companies from taking anti-tobacco positions as possible violation of laws, 355

brain

nicotine effects on, 92 , 95 -96, 315 -316

See also Central nervous system; Electroen-cephlogram

brands of cigarettes. See Cigarette brands; and by specific brand name

British American Tobacco. See BAT

British Industry Biological Research Association (BIBRA), study of coumarin, 221 -222

broadcast ad ban

benefits to industry, 262

circumvention by product placement on A-Team , 374

circumvention by R. J. Reynolds' use of Winchester little cigars, 259

consumption of cigarettes, effect on, 258

bronchitis

noninhalable cigarette, 130

smoking as cause of, 112 , 132

Brown and Williamson

document review project, 15 -16

relationship with BAT, 2 , 5 -6

sued University of California, 10 -11

Brown and Williamson documents

CD-ROM version of, 3 , 11 , 447

document review project, 7 , 15 -16, 249

litigation, discovery of documents for use in, 235 -236

source. See Butts, Mr. (Name Index)

World Wide Web, documents placed on, 3 , 11 , 447

Brown and Williamson Tobacco Corporation v Regents of the University of California , 10

burning. See Pyrolysis

business of selling nicotine, 74

Butler v Philip Morris , 10 , 236

C

CA Blockers

additives to reduce nitrosamines, 147

threat to tobacco companies, 148

CAC. See Chairman's Advisory Committee

caffeine, additive, 136 -137

California

California Action Plan, 421

California Energy Commission, presentation by Theodor Sterling, 300

early efforts to pass nonsmokers' rights law in state legislature, 416

Proposition 5. See Proposition 5

Proposition 10 , 352 , 428 -431

voter initiative, 416 -417

Californians Against Regulatory Excess

ad hominem attacks against James White, 430

tobacco industry group formed to oppose California Proposition 10 , 429

Californians for Common Sense

chairmen, nominal, 421

tobacco industry group formed to oppose California Proposition 5 , 197 , 417

use to hide industry involvement in California Proposition 5 campaign, 420

Camel cigarettes

advertising claims, 28

low-nicotine delivery, 29

problems created by existence of less toxic cigarette, 440

campaign contributions, from Tobacco Institute, 363

Canadian Tobacco Manufacturers Council, funding of McGill University, 142

cancer

Batflake, 165

CTR special projects and consultancies, 329 -337

inhalation


516

cancer (continued )

—relationship to, 81

—tests in animals, 249

legal liability for, 268

mouse skin-painting tests for, 108

red light tests for, 302

tobacco substitutes, as cause of, 165

tobacco tar, as cause of, 4

See also by specific type of cancer

cancer scare, low-tar cigarettes as response, 25

Cancer in Focus , CTR special project, 333

carbon dioxide, use to expand tobacco, 136

carbon monoxide

additives, effect of, 19

Batflake, 165

cardiovascular system, effects on, 97

CTR special project, 332

design specification, 168

environmental tobacco smoke, 22 , 353 , 402

filtering out, desirability of, 135

health dangers of, 19

modified sidestream cigarettes, 409

political relevance of medical opinion on, 141

public relations impact, 353

putting shredded dried stems in cigarettes, effect of, 168

pyrolysis, 210

reducing delivery of, 130 , 167 -168

reducing tumorgenetic activity, effect on carbon monoxide production, 136

carcinogenicity

bioassay, 21

Chemosol, as reducing, 211 -216

cigarette design, effects on, 145

cocoa, as increasing, 220

different kinds of cigarettes, 137 -138

evaluating, 152

freon, 217

lawyers, avoiding studies of, 303

legal liability, effects on, 268

menthol, 227

mouse skin-painting tests for, 133 , 153

Penar, 205 , 208

phenols, 111

processed cigarette leaves, 145

pyrolysis products of additives, 229

tobacco composition, effects on, 133

carcinogens

coumarin, 221 , 223

mouse skin painting does not detect all, 204

nitrosamines in tobacco, 143

removal from cigarette smoke, 52 -53, 117

smokeless tobacco, 313

cardiopulmonary lesions, CTR special projects, 334

cardiovascular disease

carbon monoxide, effects on, 97

CTR special projects and consultancies, 318 , 328 , 329 , 332 , 334

environmental tobacco smoke, 392

Friedman study funded by CTR as finding smoking dangerous, 323

Harvard Medical School study for industry, 255

nicotine, effects on, 78 , 82 , 97

noninhalable cigarette as protection against, 130

political problem for industry, 247 -248

quitting smoking, reduction of heart disease as negative development for industry, 352

Seltzer, Carl, CTR special project to create controversy, 294

Surgeon General's 1964 report, 18 , 19 , 49

threat to industry, 247 -248

tobacco industry research results as raising concern about, 72 -73

careless statements by Brown and Williamson scientists, 271

Carlton cigarettes, use of smoking-and-health controversy for advertising advantage, 259

Carreras Tobacco, You MaySmoke , 174

cars, as payment for product placement, 370

cash, for product placement, 370

Castano v American Tobacco , 236

causality

CTR special projects, 332

different legal situations in Britain and US, 340 -341

excessive demands for proof of, 436

individual- versus population-based conclusion, 441 -442

legal versus scientific issues, 441 -442

lung cancer, denial of link to smoking, 186

tobacco industry arguments against, 342 -343

Tobacco Industry Research Committee position on, 36 , 39

versus statistical association, 341 , 342 -343

CD-ROM, to obtain Brown and Williamson documents, 3 , 11 , 447

Celanese Fibers

analyzed cigarette smoke from various brands, 154

filter development, 154

cellulose, Viceroy filters, 29

cellulose acetate filter, health guard tip, 31

Center for Indoor Air Research (CIAR), similar to Council for Tobacco Research, 412

central nervous system

Council for Tobacco Research, 286

eugenol, effect on, 220

nicotine, effects on, 61 , 66 , 68 , 82 , 85 -87, 94 , 95 -96

Philip Morris, 286

rapid delivery of nicotine, 79

See also Nicotine addiction

cerebrovascular disease. See Stroke

Chairman's Advisory Committee

R&D cost- and risk-pooling agreements, 282 -284

sidestream smoke, 405

tobacco companies, 280

Chase Bank, industry concerns with stopsmoking clinic, 355

Cheaper to Keep Her , product placement in, 390

Chelwood Research Conference (1972), mouse skin painting, 135 -136

Chemical Research and Development Corporation, marketing Chemosol, 212

Chemosol

additive to reduce carcinogenicity, 211 -216

American Chemosol Corporation, marketed by, 212

American Tobacco, 213

antitrust implications, 285

benzo(a)pyrene, reduced by, 212 -216

Binding, Max, developed by, 212

Chemical Research and Development Corporation, marketed by, 212

congressional hearings on, 213

cooperative effort, 233


517

Council for Tobacco Research, 212

Covington and Burling, 213 -216

flowebin, original name, 212

Hazleton laboratory, tests in, 213

High Tor Foundation, 212

lawyer representing Tobacco Institute, coordination of research by, 213 -216

Lorillard, 213

marketing of, 212

Philip Morris, 213

R. J. Reynolds, 213

reduced carcinogenicity of cigarette smoke, 211

research coordinated by Tobacco Institute lawyer, 213 -216

Chesterfield cigarettes, claim of low-nicotine delivery, 29

chewing tobacco

alternative to cigarettes because of declining social acceptability, 84

diethylene glycol, 225

children

denial that industry seeks to attract, 161

educational programs to prevent problem for industry, 247

legislation to curb smoking among children, negative development for industry, 353

Kool advertisements at Snow White and the Seven Dwarfs , 363 -364

passive smoking, 22 , 392

price of cigarettes affecting smoking rates of, 249

taxation, effect of, 249

chromosomal abnormalities

Microbiological Associates, 302 -303

test used by Food and Drug Administration, 303

chronic bronchitis

irritation, 115

Surgeon General's 1964 report, 18 , 49

chronic obstructive lung disease. See Chronic obstructive pulmonary disease

chronic obstructive pulmonary disease

deletion from industry scientific report, 351

smoking as cause of, 115

Surgeon General's report, 19

CIAR (Center for Indoor Air Research), similar to Council for Tobacco Research, 412

cigar smokers, nicotine absorption via mouth, 78

cigarette brands

Ames test to rank, 148

biological activity of different brands, 152 -153, 160 -161

mouse skin-painting test to compare, 149

pesticide residues in different brands, 209

See also League tables; and by specific brand name

cigarette design

additives, 211

biological activity, as affected by, 130 , 131 , 142 , 150 , 154

carbon monoxide, level affected by, 168 , 409 -410

carcinogenicity, affected by, 145

Food and Drug Administration, 84 , 147

health concerns, design as response to, 93

humectants, 211

Imperial Tobacco (UK), 96

inhalation tests, 249

Kronberg Research Conference, 132

mutagenicity, 142

nicotine

—delivery, 93 , 96

—effects on electroencephalogram used in, 86

nothing artificial added, 218

"safe" cigarette, 138 , 160

sidestream smoke, 151 , 399 , 400 , 401 , 402 , 403 -404, 405 -406, 407 , 409 -410

smoke effectiveness increased by, 92

smoker compensation, 142

toxicity, reduced by, 136

ventilation, effects on carcinogenicity, 145

See also Reconstituted tobacco

cigarette paper, fortified with nicotine, 124

cigarette smoke. See Smoke

cigarette-smoking machines, defeating with Barclay cigarettes, 89

Cigarette Labeling and Advertising Act (1965), 175

Cigarettenfabriken (Germany), and BAT, 5

cigars, little, competition with cigarettes, 81

ciliastasis

measure of biological activity, 130

test developed by Battelle Memorial Institute, 151

Cinema Concepts, Snow White and the Seven Dwarfs controversy, 364

Cineplex Theatres, Kool Jazz advertisements, 387

cinnamaldehyde, additives, 227

Cippolone v Liggett Group, Inc. , 265

Civil Aeronautics Board

Aviado, Domingo, 309

hearings on smoking in aircraft as negative development for industry, 353

passive smoking, 248

Trans World Airways, 355

clove cigarettes, 219

cloves, eugenol as active ingredient, 219

CO. See Carbon monoxide

Cobb Theatres, Kool Jazz advertisements, 387

Coca Cola, product placement in Superman II , 367

cocaine, comparison to nicotine, 15 , 101

cocoa

additive, 220 -221

banned (temporarily) by British government in tobacco products, 220

Lorillard, 220

Philip Morris, 220

R. J. Reynolds, 220

Cohen Committee, 273

COLD (chronic obstructive lung disease). See Chronic obstructive pulmonary disease

Committee of Counsel

additives, 229

freon, 218

grass-roots lobbying, 251 -252

Tobacco Working Group, 156

"Up from the Bomb Shelter," 260

workplace smoking, 250 -251

communication between laboratories, restricted by special legal agreements, 131 -132

compensation, smoker. See Smoker compensation

Comprehensive Smoking Education Act, and additives, 226

Comprehensive Smoking Prevention Act of 1982, 318

Congress

Aviado, Domingo, testimony, 309

Comprehensive Smoking Education Act, 226


518

Congress (continued )

Comprehensive Smoking Prevention Act of 1982, 318

filters, inquiry regarding, 55

Healthy Buildings International, investigation of, 412

Johnson, James (R. J. Reynolds) testimony of, 173

Kentucky Tobacco and Health Research Institute, testimony of, 316

media coverage of proposed legislation, as influenced by industry, 356

outgunned by industry, 256 -257

regulation of tobacco by, stopping, 256

Seltzer, Carl testimony criticizing MRFIT, 295

Sterling, Theodor, testimony of, 297 , 299 , 300

tobacco superfund legislation, as possibility if unfavorable products liability ruling, 276

constitutional hypothesis

CTR special project, 335 , 350 -351

disproved by Friberg, Cederloff, and Lundman, 350 -351

Fisher, Sir Ronald A., development of hypothesis by, 186

Sterling, Theodor, CTR special project, 296

twin studies disproved, 350 -351

consultancies

definition, 289

recipients of, 328 -338

Consumer Products Safety Commission

freon, 217 , 218

jurisdiction over tobacco, 248 , 256

threat to industry, 248

Consumer Reports, exposing True magazine article, 179

Consumer Union and tar derby, 28

"Controversy on Smoking and Health--Some Facts and Anomalies," rewriting, 346 -352

controversy. See Creating controversy

COPD. See Chronic obstructive pulmonary disease

Cornell, Leonard, Addiction Research Foundation, 304

coronary artery disease. See Cardiovascular disease

coronary heart disease. See Cardiovascular disease

corporate diversification, to minimize potential financial problems of industry, 254

cost- and risk-pooling agreement

between B&W and BAT, 282 -284

liability issues, 242 -243, 284

coumarin

additive, 221 -223

Additives Guidance Panel, 221

cancer, 221 , 223

Food and Drug Administration, ban on coumarin in foods, 222

Hunter Committee, 221 -222

liver damage, caused by, 221

not on list of cigarette additives released by cigarette manufactures in 1994, 223

Now cigarettes, 222

R. J. Reynolds, 222

Raleigh/Fiesta flavor package, efforts to remove coumarin from, 222

tobacco substitutes, not recognized as safe by Food and Drug Administration, 223

tobacco substitutes, recognized as safe by FEMA, 223

Vantage cigarettes, 222

Council for Tobacco Research

Addiction Research Foundation, lack of interest in, 304 -305

antitrust issues, 285

attempt to remove acknowledgment of CTR funding of study of glycoproteins, 397

Center for Indoor Air Research, 412

central nervous system research, 286

Chemosol, 212

early response to evidence linking smoking and cancer, 26

environmental tobacco smoke, countering dangers of, 391

finding scientists to assist in lawsuits and legislation, 44

founding, 17

fraud, 326 -327

hoax, 240

inhalation studies by, 301 -304

lawyers, role of, 36 , 46

Microbiological Associates contract with, 301 -304

nicotine-blocking agents, 286

nicotine substitutes, 286

passive smoking, health evidence on, 410 -412

political function of, 44

problem created by grantee finding that cigarette smoking causes cancer, 288

public policy, support of industry position by, 317 -318

public relations role of, 17 , 44 , 240 , 254 -255, 317

publication policy of, 317 , 321 -322

Rothschild, Henry, special projects, 290 -293

"safe" cigarettes, 128

Seltzer, Carl, special projects, 290 , 293 -296

Sommers, Sheldon, 20

special account 4, 289

special account 4 administered by Jacob, Medinger, and Finnegan, 251

special account 5, 289

special project disproving constitutional hypothesis, 350 -351

special projects, 44 , 240

—and consultancies, recipients of, 328 -338

—list of, 328 -338

—to produce good publicity for industry, 317

Sterling, Elia, special project, 301

Sterling, Theodor, special projects, 290 , 296 -301

Tobacco Industry Research Committee, original name, 32

undesirable research results, insulating industry from, 45

"unfavorable" results on cardiovascular disease, 335

See also Special projects; Tobacco Industry Research Committee

Council of State Governments, Tobacco Institute support, 385

counteradvertising, 262

Covington and Burling

additives, disclosure of, 229 -231

fire-safe cigarettes, 252

freon, 218


519

grass-roots lobbying, 251

workplace smoking, 250 -251

creating controversy

American Medical Association, role in perpetuating controversy, 181

cancer causes, 169 , 185 -186

Carlton cigarette, marketing of, 259

"Controversy on Smoking and Health--Some Facts and Anomalies," 346 -352

effort to stimulate controversy in the media, 358

environmental tobacco smoke, 317 -321, 342 , 353 , 392 , 413 -416, 424 , 428 -430

filters as response, 254

government regulation, defeat of, 253 -259

health effects of smoking, 31 , 171 , 274

heart disease and smoking, 294

industry support of scientific research, 254 -255

low-tar cigarettes, value for marketing, 343

Now cigarettes, marketing of, 259

physicians, 359

public relations strategy, 353

public versus private views, 188 -189

recognition that smoking caused disease not an area of scientific controversy, 139

Royal College of Physicians report, 40 -41, 47

scientific research, to promote controversy, 254 -255

scientific statements, editing of, 347

smokeless tobacco, 313

Tobacco Industry Research Committee, 319

True cigarettes, marketing of, 259

value of controversy to industry, 190 -191

Vantage cigarettes, marketing of, 259

See also Public relations

credibility, of industry, 426

crime/fraud exception. See Work product rule; Fraud exception

CRS (cut, rolled stem), 110 , 130

CTR. See Council for Tobacco Research

cyanide, in cigarette smoke, 154

cyclamates, 248

cytrel, tobacco substitute, 137 -138, 164

D

D-Limonene, additive, 227

Dade County, Florida, nonsmokers' rights initiative, 352 , 428

dangerous, biological research, 167

Davis Theatres, Kool Jazz advertisements at, 387

Dawkins Committee, 273

DDT

residues and samples from the US tobacco crop, 209

tobacco exempted from regulations on, 210

deadwood documents

avoidance of lists of, 235 , 246

documents, 246 -247

shipment of offshore, 235 , 237 -38

death, tobacco compared to other causes, 437

deer tongue. See Coumarin

defensive research, environmental tobacco smoke, 399

DEG. See Diethylene glycol

deMaurier Light King Size cigarette, human versus machine-smoking results, 150

denial

industry desire to attract kids to smoking, 161

nicotine as addictive, 59

Department of Agriculture

limited regulatory authority, 203

Penar, 206

pyrolysis products, 228

sucker control committee, 203

support of industry, 257

Department of Health and Human Services, pressure to disclose additives, 229 -230

dependence, equivalence of addiction, 58

destroying the data, 230

diethylene glycol (DEG)

Additives Guidance Panel, 224

automotive antifreeze, 223

chewing tobacco, 225

humectant, 223 -225

not generally recognized as safe, 225

not on list of additives released by industry in 1994, 225

difficulties with inhalation tests, 134

diligence, problems created by phenol crisis, 121

dimethyldodecyalmine acetate. See Penar

dimethylnitrosamine, produced from Penar, 206

disclosure, different positions regarding additives, 229 -231

discovery, avoiding

attorney-client privilege, 241

Brown and Williamson documents, 235 -236

deadwood documents, 238 , 246 -247

definition, 236

destroying the data, 230

knowledge, 167 , 235

R&D risk- and cost-pooling agreements between B&W and BAT, 284

research overseas, 152 , 267

scientists' statements, 275 -276, 281

special procedures for handling scientific documents, 241 -246

special projects, 240

work product rule, 236 , 241

document review project, 7 , 15 -16, 249

dose. See Cigarette design; Nicotine

Douglas v US Tobacco , 313

drug delivery device

benefits of cigarettes as, 61

See also Ariel; Cigarette design; Premier

drug, definition under Food, Drug and Cosmetic Act, 59

Duck Key, Florida Research Conference (1974)

environmental tobacco smoke, 395

selective filtration, 136 -137

short-term bioassays, 153

tobacco substitutes, 164

Dugan/Farley Communications Associates, marketing research on physicians and low-delivery cigarettes, 359 -360

E

Eagle Star (UK), and BAT, 5

Eclipse, 440

economic pressures, to keep companies from adopting anti-tobacco positions, 355

Economic Research Associates, production of economic cost report favorable to industry in Proposition 5 campaign, 422

economics

Shook, Hardy, and Bacon, 336

Proposition 5, 355

smoking and absenteeism, 335 -336

Wharton study on financial impact of tobacco (1980), 353

education, as threat to industry, 247


520

electroencephalogram, effects of nicotine, 86

emminent

physicians, 187

scientists, 173

emphysema

caused by smoking, 132

legal liability for, 268

noninhalable cigarette to protect against, 130

Surgeon General's 1964 report, 49

Entity, product placement in, 390

Enviro Control, Inc., contractor for National Cancer Institute "safe" cigarette project, 160

environmental issues

freon, 217 -218

passive smoking as air pollution, 393 -394

environmental tobacco smoke

additives to affect, 403 -404

air pollution, 22

American Cancer Society study misrepresented, 351 , 385

American Heart Association, 384

arguments, same as active smoking, 342

asthma, 318

Aviado, Domingo, 308 , 309

biological activity, 152 -153, 401 , 406

carbon monoxide, 353

children, 392

cigarette design impacts on, 403 -404

constituents, harmful effects of, 395

Council for Tobacco Research

—special account 4, 251

—special projects and consultancies, 328 -338

defensive research, 399 , 407 -408

early history, 391 -393

Environmental Protection Agency, 392 , 416

Garfinkle, Lawrence, study misrepresented, 351 , 385

glycoproteins, 396 -397

health effects of, 410 -411

heart disease, as caused by, 392

industry conferences, 351

industry denials of harmful effects of, 23

London underground, banning of smoking on, 412 -413

lung cancer

—as caused by, 351 , 353 , 392 , 400

—evidence accepted by some industry consultants, 415

lung function, effect on, 428 -429

marketing cigarettes, 375

misrepresentation of Lawrence Garfinkel/American Cancer Society study, 351 , 385

National Academy of Sciences/National Research Council report, 392 , 430

nitrosamines, 398 , 403 -404

Occupational Safety and Health Administration, 416

public places, smoking in, 407 -408

public relations aspects of, 352 -353

public versus private statements of industry, 22

pulmonary function, effect on, 352

refuting scientific evidence indicating dangers of, 391

research goals, 391 , 433

Response Analysis Corporation, 311 -312

Rylander symposium, 309

Salvaggio/Lehrer Project, 318

sick building syndrome, 410 -411

sidestream smoke, reduction of, 403 , 405

sidestream smoke versus mainstream smoke, 391 -392

smoking restrictions, support for, 423

social acceptability issue, 392

special account 4, 306 -307

Sterling, Theodor, 296 -301, 320

Surgeon General's 1986 report, 22 , 392

Tobacco Institute, selection of homes for study of, 411

ventilation, 333

Vienna Conference, 351

See also Nonsmokers' rights; Passive smoking; Sidestream smoke; Social acceptability

Environmental Protection Agency

attacks on, xiv , 188 , 416

Aviado, Domingo, member of EPA Clean Air Advisory Committee, 308

EPA Science Advisory Board contrasted with industry established committees, 325

freon, 217

indoor air pollution, 436

report on passive smoking, 392

Sterling, Theodor, criticized EPA, 298 -299

tobacco smoke as air pollution, 436

epidemiology

determining total deaths caused by smoking, 441 -442

relative safety of tobacco products, 139

esophageal cancer, Surgeon General's report, 19

ETS. See Environmental tobacco smoke

eugenol

additive, 219 -220, 227

anesthetic, 210 -211

clove cigarettes, 219

cloves, active ingredient in, 219

inhalability of smoke, 219

National Cancer Institute study of, 227

nicotine, interaction with, 220

numbing of the throat, 211

pharmacology, 220 , 233

Eve cigarettes, product placement in Supergirl,368

expanded tobacco

freon, 136 , 216 -218

G-13 process, 217 -218

sidestream smoke production, to reduce, 409

toxicity effects of, 136

See also Freon; G-13

experts, financed by special account 4 , 305

export subsidies, 257

extractable nicotine

additives, to control, 81

boosted with PEI, 83

determinants of, 78 -79

filter modifies, 153

high-nicotine content tobacco, 85

mouth, absorption in, 78

PEI, 81 , 83

pH effects, 80

See also Cigarette design; Nicotine; Nicotine delivery

F

Fact cigarettes

acetaldehyde, 154

acrolein, 154

Medical Communications Program, 362

nitrogen oxide, 154

physicians, presentation to, 359 -360


521

Fairlane Theatres, Kool Jazz advertisements, 387

fairness doctrine, use by industry, 262

Farmers Group, subsidiary of BAT, 5

Fate of Nicotine in the Body,15 , 65 -68, 74

FCC. See Federal Communications Commission

federal government, misallocation of prevention resources, 437 -439

Federal Aviation Agents Administration, supporting anti-smoking forces, 257

Federal Communications Commission

anti-smoking forces, support of, 257

electronic advertising of cigarettes, restriction on, 193

jurisdiction over tobacco as limited, 256

Federal Trade Commission

advertising restrictions, attempts to impose, 260 -261

anti-smoking forces, support of, 257

Austern, H. Thomas, represented industry before, 214

carbon monoxide, 168

--testing as negative development for industry, 353

jurisdiction over tobacco as limited, 256

nicotine deliveries reported, 91

reports as negative for industry, 352

Roper Organization study for Tobacco Institute, 392 -393

smoker compensation, 89

Surgeon General's 1964 report, response of, 173 , 175

tar, concern with, 122

voluntary agreement with industry, 28

voluntary publication of tar and nicotine ratings in cigarette advertising, 254

FEMA (Flavor and Extracts Manufacturers Association), justification for using cigarette casing and flavoring ingredient, 228

fertility, in rats exposed to different kinds of cigarette smoke, 144

fetal effects

special account 4 special project, 329

Surgeon General's report, 19

Fican-Plus, insecticide, 210

Fiesta, coumarin, 222

Fifth World Conference on Smoking and Health, attended by Domingo Aviado for industry, 309

50/50 , product placement in, 367

film promotion. See Product placement

filter

acetaldehyde, 154

acrolein, 154

actron, 279 -280

additives, 154

Avalon, 71 , 72 -73

biological activity, effects on, 152 -153

boosting of nicotine delivery, 124

carbon monoxide, 130 , 135

Celanese Fibers Company, 154

cigarette toxicity, effects on, 123 -124, 126

congressional inquiry about effectiveness of, 55

Fact cigarettes, 154

health guard, 29 , 31

human smoking patterns, 141

Kent cigarettes, 119 -121

legal dangers of aerosol testing, 244

Life cigarettes, 153

magnesium oxide, to reduce visible sidestream smoke, 403 -404

Medical Communications Program, 360 -362

nicotine delivery, effects on, 124 , 27

PEI, 124 , 153

phenols, 111 , 216

physicians, presentation to, 359 -360

polyethylene glycol, 124

product design, 137

purite (in Fact cigarettes), as presented to physicians, 360

Reader's Digest evaluation of filter cigarettes, 30

selective filtration, 120 -121

sidestream smoke, 399 , 403 -404

smoking-and-health controversy, as response to, 254

tar delivery, effects on, 109

titanium dioxide, 227 , 228

Viceroy health guard filter, 29

fire-safe cigarette

antitrust issues, 252 -253

Aviado, Domingo, 308

Capri cigarettes, 252

competitive aspects, 142

instructions for coding, 249

International Association of Fire Chiefs' support of industry position, 252

Kentucky Tobacco and Health Research Institute, 316

legislation, 252 -253

Moakley, Congressman Joseph, 252

More cigarettes, 316

Nat Sherman cigarettes, 316

news stories as negative development for industry, 352

preemption, 253

Rupp, John, 252

sidestream smoke, 406

Technical Advisory Group, 252

trade secrets, 253

fires, caused by cigarettes, 142 , 252

First Amendment, applicability to cigarette advertising, 261 -262

First Blood, product placement in, 390

Flavor and Extracts Manufacturers Association, justification for using cigarette casing and flavoring ingredient, 201 , 228

flavors. See Additives

Florida

State of Florida v American Tobacco Company,9 , 236

defeat of Dade County nonsmokers' rights initiatives in 1978, 352

Floridians Against Increased Regulation (FAIR), industry group formed to oppose local clean indoor air ordinance, 428

flowebin. See Chemosol

flue-cured tobacco, compared to Batflake, 165

FLW Theatres, Kool Jazz advertisements, 387

Food and Drug Administration

acidity, for nicotine delivery, 94

addiction, regulatory implications, 102 , 103

attacks on, xiv , 181

carcinogenicity, tests for, 288

chromosomal abnormalities, test for, 303

cigarette product design, 84

cigarettes and addiction, investigation of, 100

coumarin

—as banned in foods by, 222


522

Food and Drug Administration (continued)

—substitutes, not generally recognized as safe, 223

generally recognized as safe, 201

industry opposition tactics, 428

jurisdiction over tobacco, 248 , 86 , 353

—as threat to industry, 248

—lack of, as plus for industry, 353

nicotine

—addiction, 345 , 436

—as a drug, 11

—regulatory requirements, 59

nicotine patch business, implications for tobacco company entering, 105

nonnicotine cigarette with nicotine added, 83

red light tests, 302

regulation of tobacco products, 59

regulatory implications of nicotine addiction, 102 , 103

regulatory issues, 81 , 286

—in cigarette design, 147

restrictions on cigarette advertising, 262

special account 4 consultancies, 329 , 335

tobacco substitutes, regulatory implications, 162

Food, Drug and Cosmetic Act, definition of drug or device, 59

Food for Peace Program, 257

Food Research Institute, sidestream smoke research, 409 -410

Fourth World Conference on Smoking and Health, as negative development for industry, 352

Framingham study, criticized by Carl Seltzer, 295

Frank Statement to Cigarette Smokers

advertisement, 34

private acceptance of dangers of smoking, 139

response to evidence smoking caused cancer, 33 -35

Tobacco Industry Research Committee, 33 -35

Truth, Project, 185

withholding information from Surgeon General's Advisory Committee, 74

Franklin Institute, CTR special project, 330 , 331

fraud exception

attorney-client privilege, 238 -239

work product rule, 237

free choice and nicotine addiction, 102 -103, 249

freon

Consumer Product Safety Commission, 217

Environmental Protection Agency, 217

expanded tobacco, 136 , 216 -218

G-13 process, 217 , 218

ozone layer, damage to, 217

phosgene, produced by burning freon, 217

products liability issues, 217

friends, buying by industry, 362 -363

frustration, feelings of, 51

FTC. See Trade Commission

fungicides, residues in tobacco, 202

future generations, concern for safety, 217

G

G-13

Brown and Williamson adopted process, 218

See also Freon

GASP, protest of Kool cigarette advertisements at showing of Snow White,363 -364

General Cinema, Kool Jazz advertisements, 387

generally recognized as safe, 201 , 228

See also Flavor Extracts and Manufacturers Association; Food and Drug Administration

Georgia Theatres, Kool Jazz advertisements, 387

glycerine, Real cigarettes, 218

glycerol, Additives Guidance Panel, 224

glycoproteins

cardiovascular and pulmonary effects, 396 -398

Council for Tobacco Research, 328 , 330 -331, 397

industry-sponsored studies found, 322

sidestream smoke, 432

Tobacco Research Council, 397

Godfather III,367

government intervention, precipitated by "safe" cigarette research, 125

government policy, influenced by CTR special projects, 323

government regulation. See Regulation

GRAS. See Generally recognized as safe

grass-roots lobbying, tax issues for lobbying by industry, 251 -252

grave crisis for industry, 50 -52

Griffith filter. See Avalon

group research conferences, attendance, 279

Gulf State Theatres, Kool Jazz advertisements, 387

gun, smoking. See Pistol, smoking

H

habit, versus addiction, 81

habituation, to nicotine, 65 , 84

Haines v Liggett Group,12 , 240

Harrogate laboratory

expanded to speed "safe" cigarette research, 124

mouse skin-painting test to evaluate carcinoginicity, 123

Tobacco Manufacturers Standing Committee, 133

Harvard Medical School

grantee, 255

special account 4 consultancy, 331

Hazleton Laboratory, testing of Chemosol, 213

HBI. See Healthy Buildings International

health concerns, designing of cigarette as response to, 93

health guard filter, on Viceroy cigarettes, 29 , 31

health-image cigarette, 26 , 103 -104, 114 , 129 -130

health-oriented cigarette, 26 , 103 -104, 114 , 118 , 129 -130

Health Effects of Involuntary Smoking, Surgeon General's 1986 report, 392

Healthy Buildings International

congressional inquiry regarding, 412

originally named ACVA Atlantic, 411

heart disease. See Cardiovascular disease

heroin, similarity to nicotine, 15 , 101

Hickman v Taylor,237

high-nicotine tobacco, 85

High Tor Foundation, testing of Chemosol, 212

Hill and Knowlton

organization of public relations campaign against emerging information on dangers of smoking in 1950s, 358


523

staff overlap with Tobacco Institute and Tobacco Industry Research Committee, 40

Surgeon General's 1964 report, planning reaction to, 50 -52

Tobacco Industry Research Committee, 33 , 39 -40

Tobacco Institute, 40

True magazine article, 179

Hilton, Project, description, 152

Hilton Head Research Conference (1968), 82 , 128 -132, 278

Hine, Inc., special account 4 research project, 331

Hippo, Projects

Ariel, 74

nicotine pharmacology, 151

Hippo I, Project

Battelle Memorial Institute, 62

Janus, Project, 143

nicotine's effect on hypothalamus, 62

Hippo II, Project

compared with industry attitudes in 1980, 344

Janus, Project, 143

nicotine

—benefits, 74

—and other tranquilizing drugs, 75

Honky Tonk Freeway, product placement in, 390

humectants

additive, 202 , 211

glycerine (in Real cigarettes), 218

make smoke milder and easier to inhale, 211

prolong shelf life, 211

propylene glycol, 218

Surgeon General's 1964 report, 224

Hunter Committe

biological testing, 164

coumarin, 221 -222

description, 165

tobacco substitutes, 163 , 166

hydrogen cyanide, pyrolysis of tobacco products, 210

hyperplasia test

Kool cigarettes, 153

Life cigarettes, 153

Viceroy cigarettes, 153

hyperplasia, short-term toxicity test for tobacco, 152

I

ICI (Imperial Chemical Industries), tobacco substitute, 162 -163

IIT Research Institute, CTR special project, 332

Imperial Chemical Industries, tobacco substitute, 162 -163

Imperial Tobacco (Canada)

BAT, relationship to, 5

marketing research, 376

smoker compensation, 88

smoking machine versus human smoking, 150

Imperial Tobacco (UK)

cigarette product design, 96

New Smoking Material, 162 -163

Penar, 205 , 207

"safe" cigarette research, 124

smoking-and-health research, 272 -273

inadequacy, feelings of, 51

Independent Committee on Smoking and Health, and coumarin, 222

Independent Scientific Committee, temporary banning of cocoa as tobacco additive, 220

Indonesia, market for clove cigarettes, 219

indoor air pollution. See Environmental Protection Agency; Environmental tobacco smoke

industry-funded research, demonstrating inhaled smoke causes cancer, 249

influencing physicians. See Physicians, influencing

INFOTAB, description, 198

inhalability

anesthetic, 219

controlling, 81

humectants, effect on, 211

sugar, effect on, 211

inhalation

laryngeal cancer, 249

lung cancer, 80 , 84 , 130

nicotine absorption, 67

respiratory disease, 80

inhalation testing

Batflake, 165

cancer, 145 , 249

Council for Tobacco Research, 285

CTR special projects, 334

difficulties of, 133

Hilton, Project, 153

laryngeal cancer, 249

lawyers, as avoiding studies of, 303

Microbiological Associates, 285

mouse skin-painting test, comparison with, 134

National Cancer Institute "safe" cigarette program, 157

initiatives, ballot, 416 -417

insecticides

cigarette smoke, 31

Fican-Plus, 210

residues in tobacco, 202

insurance companies, owned by BAT, 5

Interbat, information exchange system, 280

International Association of Fire Chiefs, 252

irritation

biological activity, 130

cancer, 115

chronic bronchitis, 115

sidestream smoke, 245 , 404 , 406 , 407

IT Corporation, Shook, Hardy, and Bacon research project, 332

J

Jacob and Medinger

filters, 55

glycoproteins, 397

Microbiological Associates, 303

Rothschild, Henry, CTR special project, 291

Smokeless Tobacco Council, 312

special account for congressional hearings, 305

special account 4, 251 , 289

Sterling, Theodor, special account 4 funding, 299

True magazine article, 180

Jacob, Medinger, and Finnegan. See Jacob and Medinger

JAMA

Brown and Williamson response to publication of articles in, 443 -445

decision to publish papers on Brown and Williamson documents, xviii , 11

Janus, Project

Battelle Memorial Institute, 125

benzo(a)pyrene as positive control, 215


524

Janus, Project (continued)

carcinogenicity of tobacco smoke, 151

collaboration between B&W and BAT scientists, 278 , 281

deadwood documents, 246

Hippo, Projects, relationship with, 143

meetings to monitor progress, 281

mouse skin painting, 113

potassium carbonate evaluated, 145

product modifications to reduce dangers of smoking, 113

results, 143 -146

sidestream smoke, 395

study of materials from B&W, 144

jewelry

Kovoloff could not remember who this was for, 388

product placement, as payment for, 370

Jinxed, product placement in, 390

Jones Hearing, public relations benefits to industry, 353

Journal of the American Medical Association. See JAMA

jurisdiction over tobacco

Food and Drug Administration, lack of jurisdiction as plus for industry, 353

political problem for industry, 248

K

Kent cigarettes

advertising claims, 29

filter, 29 , 119 -121, 154

nicotine delivery of, 54

Kent Golden Lights cigarettes, smoke constituents of, 154

Kent Theatres, Kool Jazz advertisements, 387

Kentucky Tobacco and Health Research Institute

applicant investigated by industry lawyers, 315

Huber, Gary, 353 , 394

lawyers, 315 -316

organization of, 314

public relations benefits, 353

Kill & Kill Again, product placement in, 390

Kippa study, of smoker compensation, 87

knowledge of research results, avoiding, 167 , 236

Kool cigarettes

advertising claims, 28 , 29

advertisement in movie theaters, 387

Body Heat, poster in, 371

cigarette ads to counter health information, 188

First Blood, product placement in, 371

hyperplasia tests, 153

Monroe case, 45

Never Say Never Again, product placement in, 371

Only When I Laugh, product placement in, 371

product placement in films, 369

Snow White controversy, 363 -364, 387

Kronberg Research Conference (1969), 82 -83, 132 -133, 268 -269

L

L&M Flavor Lights cigarettes, smoke constituents of, 154

labor

alliances with industry, 419

Jerry Brown, convincing to take neutral position on California Proposition 5 , 419

LAM Theatres, Kool Jazz advertisements in, 387

Lark cigarettes, in License to Kill , 368

laryngeal cancer

inhaling tobacco smoke as producing, 249

Surgeon General's 1964 report, 18

law firm accounts, definition, 289

lawyers

additives, 226 -228, 232

Brown and Williamson response to JAMA articles, 444

Chemosol research, 212 , 213 -216

Council for Tobacco Research, 36 , 251 , 288 , 301 -304

CTR research showing smoking causes cancer, 288

deadwood documents, 246

differences between US and UK, 345 -346

guidelines for keeping nontobacco companies from taking anti-smoking positions, 355

industry positions, developing, 198

Kentucky Tobacco and Health Research Institute, management of, 315 -316

Kronberg Research Conference, 268

Microbiological Associates CTR contract, 301 -304

Proposition 5, 420

public relations, 194 , 215 , 352 -354

restricting communication between laboratories, 131 -132

rewriting scientific documents, 346 -352

Rio, Project, 146

St. Ives Research Conference (1970), 268 , 269

scientific research, 4 , 5 -6, 21 , 128 , 212 , 236 , 265 -267, 268 -271, 311 -312

—encouragement of, to refute dangers of tobacco, 288

scientists, relationship with, 128 , 266 -267

screening scientific documents, 241 -246

Smokeless Tobacco Council research projects, selecting, 312 -313

smoking-and-health activities, involvement in, 266

special accounts 4 and 5, 305 -306

Surgeon General's 1964 report, strategies for dealing with, 52 -56

Tobacco Industry Research Committee, 36

league table, based on Ames test, 20

legal liability, and truth, 4

legislation

Cigarette Labeling and Advertising Act (1965), 175

Comprehensive Smoking Education Act, 226

Comprehensive Smoking Prevention Act (1982), 318

Council for Tobacco Research, influence on, 44 , 289

nicotine content, 247

problems caused by industry-funded research demonstrating smoking causes cancer, 288 , 302

product placement of cigarettes in films, outlawing of, 368

less hazardous cigarettes. See "Safe" cigarette

Less Hazardous Cigarette Committee

MH-30, 205

Penar, 205

Tso, T. C., 207


525

liability

avoiding attribution of BAT research to B&W, 266 -267

Council for Tobacco Research

--research showing smoking causes cancer, 288

--to find scientists to support industry positions, 44

differences between Britain and US, 340

fire-safe cigarette research, 252 -253

industry scientists' statements, 268 -271, 347

nicotine addiction, 344 -345

passive smoking, 251

phenols, failure to warn, 121

public relations, 339

R&D risk- and cost-pooling agreements between B&W and BAT, 284

"safe" cigarette research, 122 , 439 -441

warning labels, as providing protection against, 54 , 342

License to Kill, Lark cigarette placement in, 368

Life cigarettes

hyperplasia testing, 153

PEI, 153

"safe" cigarette, 125

Life magazine, reporting of early studies on smoking and cancer, 25

Liggett and Myers

Addiction Research Foundation, 304

additives, position on disclosure of, 229

annual pesticide meeting, 209

cancer, appearing to admit smoking causes, 45

G-13 process for expanding tobacco, 217 , 218

product placement in Supergirl , 368

Proposition 5 , 420

smoke from cigarettes, 154

Tobacco Industry Research Committee, 33

Tobacco Working Group, 155

Washington University site visit, 311

lip cancer, Surgeon General's report, 19

litigation. See Lawyers; Liability

London Research Conference (1979), 140 -141

London underground, banning of smoking on, 412 -413

Long Island Tobacco Co., Inc. v Lindsey,250

Lorillard

Addiction Research Foundation, 304

additives, disclosure of, 229

advertising claims for Kent cigarettes, 29

annual pesticide residue meeting, 209

Chemosol, 213

cocoa, replacement with proprietary substitute, 221

G-13 process to expand tobacco, 217

Kent micronite filter, 154

phenols, reaction to selective removal, 216

Proposition 5 , 419 , 420

smoke from cigarettes, 154

Time, Inc., meetings to influence coverage of Surgeon General's 1983 report, 356

Tobacco Industry Research Committee, 33

Tobacco Working Group, 155

workplace smoking, favoring study of, 251

Louisville Courier, articles as negative development for industry, 352

Love Child, product placement in, 390

low-delivery cigarette

advantage for industry, 353

alternative to quitting, 339

biological activity, 142

creating controversy, 343

cigarette consumption, effects on, 90

health concerns, as response to, 25 , 26 -28, 274

marketing, 161 , 245

Medical Communications Program, 360 -362

paradox of production when claiming smoking does not cause disease, 343

physicians, 90 -91, 360 -362

smoker compensation, 88

low-sidestream product, demand for, 409 -410

lubricants, residues in tobacco, 202

Lucky Strike cigarettes

advertising claims, 28

Foote, Emerson, 178

lung cancer

alternative explanations, 342 -343, 352

carcinogens, dose in smoke, 91

countering evidence of smoking as cause of, 188 -189

CTR special projects, 291 -293, 329

denials of relationship to smoking, 172 , 181 , 184

early studies of, 25

environmental tobacco smoke, as cause of, 22 , 351 , 392 , 400 , 408 , 413 -416

Environmental Protection Agency, 416

Harrogate laboratory research, 113

inhalation, 80 , 84 , 130 , 301 , 301 -304

irritation, 115

media coverage of early scientific studies, 25

Microbiological Associates inhalation study, 301 -304

mouse skin-painting test for, 21 , 25

nitrosamines, 398

public relations, 18 , 352

public versus private statements of industry as to causes of, 18

Royal College of Physicians study of, 26

smoking as cause of, 132

Surgeon General's 1964 report, 18 , 22 , 26 , 48

Surgeon General's 1972 report, 19

Tobacco Research Council, 152

ZEPHYR , as code name for, 109 -110

lung disease, Harvard Medical School investigations for industry, 255

lung function, effect of passive smoking, 428 -429

M

Maddox v Williams,1 , 8 , 9 , 13 -14, 239

mainstream smoke

definition, 391 -392

nitrosamines, 403 -404

Making Love, product placement in, 390

maleic hydrazide. See MH-30

Mann Theatres, Kool Jazz advertisements in, 387

manufacturing techniques. See Cigarette design

marketing

Ariel's potential position, 74 -75

low-delivery cigarettes, 161 -243

social acceptability of smoking, 339

Marlboro cigarettes

Apocalypse Now, product placement in, 372 -373

Body Heat, product placement in, 371

Superman II, product placement in, 367 , 368 , 372

Martin Theatres, Kool Jazz advertisements in, 387


526

Matinee Extra Mild, relationship between human and smoking-machine results, 150

McCann-Eriksen Advertising Agency, 178

McDonnel and Company, agents for owners of Chemosol, 212

McGill University, research on smoke quality, 142

McKennell-type test, 87

McNeil/Lehrer news program, 295

MCP. See Medical Communications Program

Meckler Engineers Group, special account 4 research project, 333

media

lung cancer, coverage of early studies, 25

meetings to influence coverage of Surgeon General's 1983 report, 356

Seltzer, Carl, CTR special projects, 294

Medical Communications Program, to influence how physicians discuss cigarettes with their patients, 360 -362

menthol

carcinogenicity of, studied by National Cancer Institute, 227

numbing of throat by, 211

Real cigarettes, 218

Merano Research Conference (1975)

new smoking materials, 137 -139

passive smoking, 395 -396

Merit, smoke constituents of, 154

MH-30

evidence of toxicity, 203

high-level residues in exports to West Germany, 210

Less Hazardous Cigarette Committee, 205

powder keg, 205

reformulated, 208

toxicity in mice, 204

Microbiological Associates

antitrust implications, 285

benzo(a)pyrene, 303

inhalation studies of tobacco smoke, 301

lawyers, as avoiding studies by, 303

Micronite filter. See Kent, filter

million-dollar offer, 186 -187

Minnesota Clean Air Act, 416

model ordinance, produced by industry, 251

monkeys, squirrel, effects of nicotine, 85 -86

Monroe case, 45

Montebello Research Conference (1982)

passive smoking, 401 -403

"safe" cigarette research, 142 -143

smoker compensation, 91 -92

Montreal Joint R&D/Marketing conference (1984)

nicotine, effects on product design, 96 -97

Rio, Project, 149

Montreal Research Conference (1967)

conclusions from St. Adele Research Conference modified, 83 -84

nicotine and addiction, 80 -82

"safe" cigarette research, 127 -128

smoker compensation, 90

morality, of using freon, 217

More cigarettes, as self extinguishing, 316

motion pictures

product placement of cigarettes in, 364 -374

Snow White controversy, 363 -364

mouse skin painting

cancer bioassay, 21 , 108 , 114 , 127 , 129 -130, 132 -133, 134 , 145

carcinogens, test as not detecting all, 204

Chemosol, 212 , 213 -216

deadwood documents, 246

early studies indicating lung cancer, 25

freon, effects on carcinogenicity of, 217

fresh versus stored condensate, 115

Harrogate laboratory capacity, 114 -115

inhalation studies and cellular biochemical studies, comparison with, 127

Janus, Project, 113 , 143 -144

legal liability, 268

National Cancer Institute "safe" cigarette program, 157

Penar increased biological activity, 208

potassium carbonate effects, 125

public attack on by industry, 118 -119, 187

public versus private statements, 33 , 133

short-term biological tests, comparison with, 151 , 152 , 153

sidestream smoke, 401

standard for testing carcinogenicity, 133

stratification of cigarette brands, not possible, 149

tobacco composition, impact of, 133

vapor phase carcinogens not tested, 204

Wynder, Ernst, 113

See also Janus, Project

movies, product placement in films to circumvent broadcast ad ban, 368 -369

MRFIT (Multiple Risk Factor Intervention Trial), criticized by Carl Seltzer, 295

Multiple Risk Factor Intervention Trial (MRFIT), criticized by Carl Seltzer, 295

mutagenicity

additives, 245

product design features, 142

smoking patterns, 142

tobacco type, 142

ventilation increases, 149

N

N-Bloctin

additive to reduce nitrosamines, 147

regulation as drug by Food and Drug Administration, 147

N-nitrosonornicotine, carcinogen in smokeless tobacco, 313

Nat Sherman cigarettes, as fire-safe, 316

National Academy of Sciences

environmental tobacco smoke report, 392

smoking restrictions in public buildings, 430

Sterling, Theodor, submitted material, 297

National Association of Counties, Tobacco Institute support of, 385

National Association of Attorneys General, Tobacco Institute support of, 385

National Association of Convenience Stores, Tobacco Institute support of, 386

National Association of Latino Elected Officials, Tobacco Institute support of, 385

National Association of Neighbors, Tobacco Institute support of, 386

National Association of State Departments of Agriculture, Tobacco Institute support of, 385

National Black Caucus of State Legislators, Tobacco Institute support of, 385

National Cancer Institute

Chemosol, 213

cocoa increases carcinogenicity, 220

eugenol, study of, 227

menthol carcinogenicity, 227

passive smoking, 384

"safe" cigarette program, rationale for, 159 -160


527

support of research leading to this book, xviii

threat to industry, 247

tobacco substitutes, 163

Tobacco Working Group, 155 -162

National Center for Initiative Review, Tobacco Institute support of, 385

National Conference of State Legislatures, Tobacco Institute support of, 386

National Interagency Council on Smoking and Health, 178

National League of Cities, Tobacco Institute support of, 386

National Legislative Services and Securities, Tobacco Institute support of, 386

National Licensed Beverage Association, Tobacco Institute support of, 386

National Order of Women Legislators, Tobacco Institute support of, 386

natural cigarettes, 218

NCI. See National Cancer Institute

Never Say Never Again

disappointment of B&W with product placement in, 373

Kool cigarettes, appearance in, 371

Winston cigarettes, appearance in, 371

New England Journal of Medicine , paper by Henry Rothschild, 292

New Jersey

Sanitary Code, proposed amendments to limit public smoking, 432

workplace smoking restrictions, 431

new smokers, denial that industry seeks to attract, 161

new smoking material. See Tobacco substitutes

New Smoking Material (NSM), 137 -138, 162 -165

New York Times , reporting early studies on smoking and cancer, 25

nicotine

a nice jolt of, 54

absorption site, 94

acetylcholine, 86

active agent in tobacco smoke, 86 -87

added to nontobacco product, 83

avoiding knowledge of pharmacology of, 245

benefits of, 60 -61, 64 , 71 , 73

brain, effects on, 87 , 92 , 315 -316

cardiovascular system, effects on, 82 , 97

central nervous system, effects on, 61 , 66 , 68 , 82 , 85 -87

cigarette design, 96

cocaine, compared to, 15

crucial element in tobacco use, 81 -82

CTR special projects, 334

diet and weight, 69

dose and smoker satisfaction, 93 -94

drug effects, 3

electroencephalogram, 86

environmental tobacco smoke, as measure of, 413

essential to use of tobacco products, 104

eugenol, 220

extractable, 78 -79

Fate of Nicotine in the Body , 65 -68

fortification of cigarette paper, use for, 124

heroin, compared to, 15

humectants, as affecting absorption of, 223

importance to industry, 98 -99

irritant in cigarette smoke, 130

market for, 243

marketing cigarettes, 375

nonextractable, 78

optimal level of, 81

other drugs, compared to, 86

overdose by smoking impossible, 61

peripheral targets, 66

pharmacology, 65 -68, 76 , 85 , 92 , 95 , 447

pituitary gland, 62 , 68

poison, 103

powder added to tobacco, 124

reason people smoke, 58 , 78 , 97 , 98 , 376

reserpine, compared to, 62 , 63 -64

"safe" cigarette research, 126

self-dosing, 69

selling of, 58

smoker compensation, 16 , 94

smoker satisfaction, 92 -94

squirrel monkeys, 85 -86

synergistic effects with other drugs, 82

taste of cigarettes, as affecting, 104

tolerance for, 63 , 67 , 68 , 69

tranquilizers, compared to, 62 , 75

tranquilizing effects, 64 , 73

uptake by smokers, 95

withdrawal, 64 , 68

—edited out of industry documents, 101 -102

See also Janus, Project

nicotine absorption, See Nicotine delivery

nicotine addiction

avoidance of warning label regarding, 59 -60

Brown and Williamson response to JAMA articles, 444

CTR not interested in studying mechanism of, 304 -305

cocaine, similarity to nicotine, 101

definition, 58

denials of, 100 , 101 , 5 , 59

dose necessary, 84

Ellis, Sir Charles, recognition of, in 1962, 60

extent, 59

Food and Drug Administration, 102 , 103 , 345 , 436

heroin, similarity to nicotine, 101

importance to industry, 58 , 97

liability for, 344 -345

mechanism, 69 , 80 , 65 -68

public versus private statements by industry, 15

Sandefur, Thomas, statement on, 105

scientists' views as causing problems in court, 344 -345

Surgeon General's Advisory Committee, withholding information from, 50

Surgeon General's reports, 15 , 58

tolerance, 63 , 65 , 67 -69

withdrawal, 65 , 101 -102

See also Janus, Project

nicotine analogues

antitrust issues, 286

Kentucky Tobacco and Health Research Institute, 316

Philip Morris, 97

safer cigarettes, 104

search for, 97

nicotine blockers, Council for Tobacco Research, 286

nicotine content

controlled, 76

potential legislative limits of, 247

reconstituted tobacco, 85

taxation on basis of, 249 -250


528

nicotine delivery

acidity, effects on, 67 , 79 , 96

addition to tobacco, 124

additives, effects on, 79 , 81

advertising claims for Kent cigarettes, 29

ammonia, effects on, 211

boost to achieve same nicotine delivery with less tar, 124

chemical form, effects on, 83

chewing tobacco and snuff, 84

determinants of, 80

device. See Nicotine delivery device

effect-type test, 87

Federal Trade Commission method, 91

filter, effects on, 27

Food and Drug Administration, relevance of manipulation, 83

form of nicotine as affecting, 80

inhalers versus noninhalers, 66

Kent cigarettes, claims, 29

low-nicotine cigarettes, 29

manipulated, 83

mouth, 78

PEI boosts, 124

pH, 67 , 79 , 96

product design to control, 137

smoker compensation, 87 , 96

sucker control agents, effects on, 203

toxicity reduced, 126

nicotine delivery device

Ariel, 62 , 65 , 74 -78, 131

Eclipse, 440

Premier, 30 , 219

nicotine enhancement

effects on human smoking behavior, 245

legal dangers of pharmacological information, 245

nicotine patch

business for tobacco companies, 105

Food and Drug Administration, 105

nicotine powder, addition to tobacco, 124

nicotine substitutes, Council for Tobacco Research, 286

Night People (All Night Long) , product placement in, 390

Nine to Five , product placement in, 390

nitrogen oxides, in cigarette smoke, 154

nitromethane fraction index (NMFI), 153 -154

nitrosamines

carcinogens in tobacco and tobacco smoke, 126 , 398 , 398

high in stems, 143

N-Bloctin reduces, 147

Philip Morris research, 143

presence in tobacco, 143

regulatory concerns, 399

sidestream smoke, 398 , 400 , 402 , 403 -404, 432

NMFI (nitromethane fraction index), 153 -154

NNN, carcinogen in smokeless tobacco, 313

nonextractable nicotine, 78

nontobacco material, relationship to nicotine delivery, 83

noninhalers, nicotine absorption, 67

nonsmokers' rights

clean indoor air ordinance produced by industry, 251

Colorado, 428

defeats viewed as positive for industry, 352

early history, 391 -393

early recognition of importance by industry, 257 -258

emergence of, 416 -417

Florida, 428

growing problem for industry, 258

Proposition 5 , 417 -428

Proposition 10 , 352 , 428 -431

Proposition P, 431

recognition that public smoking restrictions are constitutional, 263

zealots, 393

North Carolina Tobacco Foundation, support of annual pesticide residue meetings, 209

Now cigarettes

coumarin used, subsequently removed, 222

smoking-and-health controversy used for marketing advantage, 259

NSM (New Smoking Material), 137 -138, 162 -165

O

Oak Ridge National Laboratory, CTR special project, 333

Occupational Safety and Health Administration

attacks on, by industry, xiv , 181 , 416

economic arguments against regulation of smoking, 427 -428

lung cancer, 416

workplace smoking restrictions, 436

Old Gold cigarettes

advertising claims, 28

low-nicotine delivery, 29

Only When I Laugh

product placement in, 390

showing of Kool and Marlboro cigarettes being bought and smoked, 371

oral cancer, Surgeon General's report, 19

organic cigarettes, difficulties making claim, 218

organized labor, role in defeating California Proposition 5 , 419

overdose, difficulty with smoking, 61

oxidants, CTR special projects, 334

ozone layer, damage by freon, 217

P

package warnings, 193

pancreatic cancer, Surgeon General's report, 19

panic, of industry with regard to 1964 Surgeon General's report, 441

paper, cigarette

fortified with nicotine, 124

sidestream smoke, effect on, 405 -406

passive smoking

airlines, 248

Brown and Williamson response to JAMA articles, 444

Civil Aeronautics Board, 248

commercial aspects, 401 -402

considered relatively unimportant (1974), 395

constitutionality of smoking restrictions, 263

damages to lung cancer victim, 251

defensive research on, 405

early recognition of importance by industry, 393 -394

Hirayama research criticized by Theodor Sterling, 299

liability for, 251

new products to respond to, 151

nitrosamines, 398

smokers' rights organizations, 252

Surgeon General's 1979 report, 384

threat to industry, 248 , 257 -258

tobacco industry model ordinance, 251


529

workplace smoking regulation, 250 -251

zealots, 393

See also Environmental tobacco smoke; Sidestream smoke

patent, Ariel, 75 -76

Paul, Weis, Rifkind, Wharton & Garrison, discovery of BAT results in US cases, 267

PCL. See Processed cigarette leaves

Peabody Museum, 293

Pearson, B. G., keeping track of scientists, 197 -198

PEG. See Polyethylene glycol

PEI (polyethyleneimine)

additive to boost extractable nicotine, 81 , 83

Avalon filter, 125

biological activity, effect on, 152 -153

filter treatment to reduce toxicity, 124

Kronberg Research Conference, 132

Life cigarette filter, 153

Penar

carcinogenicity, 205 , 208

chromosome aberrations in plants, 203 -204

dimethylnitrosamine produced, 206

Imperial Tobacco (UK), 207

Less Hazardous Cigarette Committee, 205

personal reassurance, of low-delivery cigarettes, 245

pessimism, in anticipation of Surgeon General's 1964 report, 51

pesticides

annual residue meeting, 209

DDT, 209

pyrolysis effects, 204

regulatory issues in West Germany, 209

residues

—in tobacco, 202

—in various cigarette brands, 209 -210

view on safety contrasted with safety of tobacco use, 207

pH

extractable nicotine, 79 , 80

nicotine

—absorption, 67 , 79 , 80

—delivery, 93 , 96

pharmacology, nicotine. See Nicotine, pharmacology

phenols

crisis, 119 -123, 126 -127

filter, 111 , 216

Philip Morris

Addiction Research Foundation, 304

additives, disclosure of, 229

annual pesticide residue meeting, 209

Apocalypse Now , Marlboro placement in, 372 -373

central nervous system research, 286

Chemosol, 213

cocoa, 220

consistent products, 137

diethylene glycol, humectant, 223

Environmental Protection Agency, attacks on, 181

G-13 process to expand tobacco, not using, 217

Marlboro product placement in films, 367 , 372 -373

nicotine analogues, 97

nicotine delivery devices compared to Ariel, 76 -77

nitrosamines, 143

product placement in films, 365 , 368 , 372 -373

Proposition 5, 419 , 420

restrictions on smoking, protest of, 188

smoke from cigarettes, 154

Superman II , Marlboro placement in, 367

Tobacco Industry Research Committee, 33

tobacco substitutes, 164

Tobacco Working Group, 155

Washington University site visit, 311

workplace smoking, restrictions on, 251

phosgene, byproduct of burning freon, 217

physicians

eminent, 187

low-tar cigarettes, promotion of, 90 -91

Scientific Perspective on the Cigarette Controversy, 358

smoking-and-disease controversy, 359

use in cigarette advertisements, 28

Pichlarn Research Conference (1981)

additives, 211

sidestream smoke, 401

smoker compensation, 91 , 141 -142

pipe tobacco, cocoa as additive, 220 -221

pistol, smoking, 45

pituitary gland, effect of nicotine on, 62

Planet cigarettes, tobacco substitutes, 163

Plitz Cinema ads, termination agreement, 373

politics

additives, 230 -231

brand advertising used to support political position, 191

carbon monoxide, 141

Council for Tobacco Research, 44 , 317 -318

nicotine addiction, 249

nonsmokers' rights initiatives, 352

preemption strategy, 253

product placement in films, 372

Proposition 5, 417 -428

Proposition P, 431

Proposition 10 , 352 , 428 -431

smokers' rights groups, 408

taxation of tobacco based on tar and nicotine content, 259

tobacco, as unpopular with politicians, 257

Tobacco Institute support, 385 -386

tobacco superfund legislation, 276

See also Proposition 5; Tobacco Institute

polycyclic aromatic hydrocarbons

additives, effects of, 144

carbon monoxide, effect of reducing, 136

carcinogenicity, used in tests of, 153 -154

carcinogens, 127

removal from cigarette smoke, 131

polyethylene glycol

Avalon filter, 125

filter additive to reduce carcinogenicity of cigarette smoke, 124

polyethyleneimine. See PEI

Post-Keyes-Gardner, Project Truth, 184

potassium carbonate, additive to reduce benzo(a)pyrene delivery, 125 , 127 , 145

powder keg, MH-30, 205

preemption

federal fire-safe cigarette legislation, 252 -253

general industry political strategy, 253 , 255 -256, 259

pregnancy, Surgeon General's report, 19

Premier

Ariel, compared to, 77

Eclipse, compared to, 440

nicotine delivery device, 30 , 219

tobacco extract used in, 219


530

preventable deaths, tobacco compared to other factors, 437

Private School , product placement in, 390

processed cigarette leaf (PCL), biological activity of, 130 , 145

product development. See Cigarette design

product placement in films

All the Marbles , 390

Alta Marea Productions, 367

Blue Skies Again , 387 , 390

Body & Soul , 390

Body Heat , 371 , 390

brands in specific films, 371

Cheaper to Keep Her , 390

Entity , 390

First Blood , 390

government safety program, 367

Harry & Son , 387

Honky Tonk Freeway , 390

Jinxed , 390

Kill & Kill Again , 390

Killing Ground , 387

Kool cigarettes, 369

legislation to outlaw for cigarettes, 368

loss of enthusiasm by Brown and Williamson for, 372 -374

Love Child , 390

Making Love , 390

Never Say Never Again , 387

Night People (All Night Long) , 390

Nine to Five , 390

Only When I Laugh , 390

Philip Morris, 365

Private School , 390

producers, active solicitation by, 367

Savannah Smiles , 390

secondary placement on video and television, 368

Shaker Run , 387

Sharkey's Machine , 390

Smokey & Bandit III , 387

specific theaters, 387

Star Chamber , 390

Summertime , 390

Supergirl , 367

Superman II , 367

Superman III , 367

Sylvester Stallone, 365 -367, 387

Tank , 387

television, 364 -365

Tempest , 387

Two for the Price of One , 390

Wacko , 390

Where the Boys Are , 387

See also Associated Film Promotion (AFP)

products liability

additives, 226 -227, 230 -231, 232 , 233

attribution of statements made by non-US BAT subsidiaries, 274

conference on, 275

definition, 264

freon to expand tobacco, 217

history, 235 , 264 -265

in-house versus contract research, 275

industry-sponsored research linking smoking with cancer, problems created by, 302

maintaining legal distance between B&W and BAT, 277

nicotine pharmacology, knowledge of as dangerous, 245

profits, adverse effect of loss of products liability case, 276

scientific research, problems created by, 6

scientists, avoiding damaging statements by, 275 -276

strategy of no settlements, 276

tobacco superfund legislation, 276

warning labels, benefits of, 54 , 255 -256

profits, adverse effect of loss of products liability case, 276

Project A, 193 -197

Project Ariel. See Ariel

Project B, 195 -197

Project Hilton. See Hilton, Project

Project Hippo I. See Hippo I, Project

Project Hippo II. See Hippo II, Project

Project Janus. See Janus, Project

Project Rio. See Rio, Project

Project Truth

countering health messages through cigarette advertising, 188

description, 184 -187

Frank Statement, 185

Tobacco Institute Communications Committee, 194

Project Wheat, 92

Proposition 5

American Cancer Society, 423 , 424

California Action Plan, 421

Californians for Common Sense, formation to shield industry involvement, 420

chairmen, nominal, 421

description of, 417

Economic Research Associates, production of economic cost report favorable to industry, 422

industry control of campaign, 421

industry veto of attacks on legislature suggested by Woodward & McDowell, 424 -425

lawyer involvement in, 420

Ligget & Meyers, 420

Lorillard, 419 , 420

Philip Morris, 419 , 420

polling results, 419 , 421 , 422 -423

potential financial impact on industry, 426 -427

public support of smoking restrictions, 425

rock concerts versus jazz concerts, 424

strategies for defeating, 417 -418, 421

tobacco industry's low profile, 418

Woodward & McDowell, management of No-on-5 campaign, 420 -421

potential financial impact on industry, 417

Proposition P, 431

Proposition 10 , 352 , 428 -431

propylene glycol

Additives Guidance Panel, 224

humectant, 218

Public Affairs Council, Tobacco Institute support of, 386

public opinion, and tobacco industry, 262

public policy. See Politics

public relations

addiction, 353

additives, 137 , 225 , 228 , 230 -231, 233

Barron's editorial, 175 -177

BAT, 339 -342

benefits of smoking, 344

birth control pills and smoking, 353

caffeine as additive, 137

cancer, countering evidence that smoking causes, 188 -189


531

carbon monoxide, 353

Chemosol, 215

contrasted with internal research, 104 -105, 133

Council for Tobacco Research, 17 , 32 -33, 44 , 254 -255, 322 -323

creating controversy, 169 , 171 , 288 , 353

Dontenwill study showing that inhalation produces cancer, 248 -249

Environmental Protection Agency, attacks on, 181

environmental tobacco smoke, 23 , 342 , 352 , 352 , 353 , 415

filter cigarettes, promotion of, 28

fire-safe cigarette, 352

Food and Drug Administration, jurisdiction of, 353

Frank Statement to Cigarette Smokers, 33 -35

health-image cigarette, 129

Hill and Knowlton, 33

hoax, 240

Huber, Gary, 353

inhalation studies, 134

lawyers, 194 , 352 -354

legal implications, 4 -5

less toxic cigarette, 118

liability, 339

low profile for industry in political campaign, 418

low-tar cigarettes, promotion of, 28

lung cancer

—alternative explanations for, 352

—and environmental tobacco smoke, 353

—public versus private statements of industry, 18

media, high-level meetings with, 356 -358

medical community, initial responses directed at, 358

misrepresentation of Lawrence Garfinkel and American Cancer Society position on passive smoking and lung cancer, 351

mouse skin painting, 21 , 127 -128, 133 , 134 , 187

nicotine addiction, 101 , 102 -103, 249

pitfalls of trying to influence media, 356 -358

Project Truth, 184 -187

Reader's Digest, problems created by, 122

Rothschild, Henry, 292 -293

"safe" cigarette research, 125

scientific evidence, approach to, 341

selling doubt, 190 -191

Seltzer, Carl, 295

special projects, 317

Superdome, 353

Surgeon General's 1964 report, attacks on, 162

Surgeon General's 1983 report, attacks on, 356

Tobacco Industry Research Committee, 32 -33, 39 -40

See also Frank statement; Physicians, influencing

public smoking

CTR special projects and consultancies, 329 , 330 , 331 , 333 , 335 , 336

See also Environmental tobacco smoke; Nonsmokers' rights; Passive smoking; Sidestream smoke

public support of smoking restrictions, 425

Public Smoking Advisory Group, 394

publication

carcinogenicity, 128

Chemosol, 215

Council for Tobacco Research credit, 317

industry control of, 126

influence on, by industry, 321 -323

lawyers' suggestions regarding scientific publication, 292 -293

manipulation of, by industry, 288

puff volume, effect on biological activity, 145 -146, 152 -153

pyridine, additives, effects on, 227

pyrolysis

additives, effects on, 201 , 211

agricultural chemicals, effects on, 204

carbon monoxide, 210

carcinogenicity, 229

hydrogen cyanide, 210

pesticides, effects on, 210

phosgene from freon, 217

Q

quitting smoking

benefits for cardiovascular system, 353

opposing efforts at Chase Bank, 355

special account 4 research project, 329

R

R. J. Reynolds

Addiction Research Foundation, 304

additives, 213 , 220 , 222 , 229

advertising claims for Real cigarettes, 218

American Cancer Society, 351 , 385

annual pesticide residue meeting, 209

Chemosol, 213

cocoa, 220

congressional testimony, 173

coumarin in Now and Vantage cigarettes, subsequently removed, 222

Eclipse, 440

Environmental Protection Agency, attacks on, 181

G-13 process, 217

Garfinkle, Lawrence, 351 , 385

nicotine delivery devices compared to Ariel, 76 -77

Now cigarettes contained coumarin, subsequently removed, 222

passive smoking and lung cancer, 351 , 385 , 415

Premier, 30 , 77 , 219 , 440

Projects A and B, 193 -197

Proposition 5, 420 , 421

smoke from cigarettes, 154

Sullum, Jacob, 181

Tobacco Industry Research Committee, 33

tobacco substitutes, 164

Tobacco Working Group, 155

Vantage cigarettes contained coumarin, subsequently removed, 222

Washington University site visit, 311

Winchester little cigar, 259

workplace smoking, restrictions on, 251

radiation, Council for Tobacco Research special project, 333

Raleigh cigarettes

billboard in First Blood,371

brand advertising to communicate health and political information, 191

coumarin, 222

Rambo, 367

Reader's Digest

early studies on smoking and cancer, 25

filter cigarettes, relative toxicity of, 30


532

Reader's Digest (continued)

public relations problems created for industry, 122

Royal College of Physicians report, 47

Real cigarettes

advertising claims, 218

menthol, 154 , 218

Reason Foundation, receipt of funds from Philip Morris, 181

reconstituted tobacco

biological activity, 130 , 131 , 145

carbon monoxide, reduction by use of, 130

enriched in Ariel cigarettes, 75 -76

high-nicotine content, 85

processed cigarette leaf, 130

red light tests

antitrust issues, 285

avoidance of, 302

carcinogenicity, 288

reduced biological activity. See "Safe" cigarette; Rio, Project

Regional Governors' Associations, Tobacco Institute support, 386

regulation

additives, 202 , 233

advertising restrictions, coping with, 408

common-sense opposition, 195

DDT, tobacco as exempt from limits on, 210

fear of, by industry, 247 , 248

federal level preferred, 259

industry research on carcinogenicity of cigarettes, 123

jurisdiction divided, 256 -257

legal challenges, 259 -263

nicotine addiction, implications of, 102

nitrosamines, 399

pesticides, 209 , 210

preemptions, as industry strategy, 259

product placement in films to circumvent broadcast ad ban, 368 -369

Robertson, Gray (Healthy Buildings International), testimony of, 412

secondhand smoke, 257 -258

smoker compensation, implications, 89 , 91

smoking machines, 91

special account 5, 329

strategies by industry to avoid, 90 , 253 -259

sucker control agents, Department of Agriculture limited authority over, 203

tar derby, benefit to industry of ending, 27 -28

tobacco substitutes, implication of, 162

West Germany and pesticides, 209

workplace smoking, 250 -251

See also Food and Drug Administration; Occupational Health and Safety Administration; Politics; Proposition 5

research, scientific. See Scientific research

research conferences

attendees, 279

Brazil (1983), 219 -220

Chelwood (1972), 135 -136

Duck Key (1974), 136 -137, 164 , 395

eugenol, 219 -220

London (1979), 140 -141

Merano (1975), 137 -139, 395 -396

Montebello (1982), 142 -143

Pichlarn (1981), 141 -142, 211 , 401

Rio De Janeiro (1983), 406

schedule, 282

Sea Island (1980), 166 -167, 400

Smoking Behavior Marketing Conference, Montreal (1984), 374 -376

Southampton (1984), 407

St. Adele (1970), 135

Sydney (1978), 138 -139, 398 -399

See also by specific research conference

reserpine

compared to nicotine, 62

Hippo II, Project, 63 -64

Response Analysis Corporation

environmental tobacco smoke, 311 -312

special account 4 research project, 334

Rhinestone Cowboy,367

Rio, Project

Ames test, 148 -149

design of cigarettes with reduced biological activity, 146 -151

general goals, 146

legal dangers, 146 , 265 -266

Rio de Janeiro Research Conference (1983)

nicotine, 94 -95

sharing of information among BAT affiliates and subsidiaries, 278 -281

sidestream smoke, 406 -407

smoker compensation, 88 -89

Rocky IV, 366 , 367

rodenticides, residues in tobacco, 202

Roper Organization, polls conducted for industry, 392 -393

Royal College of Physicians report

debate over industry response to, 26

industry response to, III, 40

public attention, 47

Scientific American,47

summary of, 46 -47

tobacco industry reaction to, 47

Tobacco Manufacture Standing Committee, attack on, 186

YouMaySmoke attacks, 174

Rylander symposium, 309

S

SAB. See Council for Tobacco Research; Scientific Advisory Board

sacchrine, 248

"safe" cigarette

Addiction Research Foundation, 304 -305

benzo(a)pyrene, reduction of, 110

carcinogenic substances, removal of, 117

Enviro Control contractor to National Cancer Institute, 160

Gori, Gio, 155

impossibility of making completely safe cigarette, 138

legal difficulties, 162 -163, 439 -441

Less Hazardous Cigarette Committee, 205 , 207

manufacturing processes, 160

Microbiological Associates, 285

motivation, 108 -109

popularization by Gio Gori and Tobacco Working Group, 155

problems created by existence of "less safe" cigarettes, 122 , 440 -441

response to Surgeon General's 1964 report, 20 , 50

Rio, Project, 146 -151

Tobacco Industry Research Committee, 53

Tobacco Working Group, 15

See also Cigarette design

safety, of pesticides versus cigarettes, 207

safrole (mace), additives, 227


533

St. Adele Research Conference (1970)

compared to conclusions at Montreal Research Conference, 80 , 83 -84

nicotine, 83 -85

"safe" cigarette research, 135

St. Ives Research Conference (1970), statements regarding causation that concern lawyers, 269

St. Regis Paper Company, industry concern that chairman was working with American Cancer Society, 355

Salem cigarettes, problems created by less toxic cigarette, 440

Santikos Theatres, Kool Jazz advertisements in, 387

Savannah Smiles, product placement in, 390

scientific controversy. See Creating controversy

scientific meetings

Aviado, Domingo, attendance at, for industry, 309

Council for Tobacco Research consultants, attendance at, 289

desirability of having industry scientists attend, 319

sponsorship by industry, 321

scientific research

attorney work product, use to avoid discovery of, 237 -238

avoiding

—disclosure of, 4

—generation of adverse results, 266

—knowledge of, 236

cost- and risk-pooling agreements between B&W and BAT, 282 -284

creation of controversy about health effects of smoking, 25

facilities established by BAT, 5 -6

Huntington laboratory experiments, 134

lawyer involvement in, 4 , 5 -6, 21 , 236 , 289

reduction of toxicity of cigarettes, 138

refutation of unfavorable findings, 254

Scientific Advisory Board

members of, 37 -39

public statements of industry regarding, 42

responsibilities of, 36

special projects, did not review, 289

Tobacco Industry Research Committee, 35 -36

See also Council for Tobacco Research; Tobacco Industry Research Committee

Scientific American, publicizing of Royal College of Physicians report, 47

Scientific Perspective on the Cigarette Controversy, to influence physicians' views of smoking, 358

scientists

careless statements by industry, 267 -271

collaboration between B&W and BAT, 277 -281

keeping track of, 197 -198

products liability, concerns about statements by, 275 -276

relationship of industry scientists with lawyers, 266 -267

Sea Island Research Conference (1980)

discouraging certain areas of research, 166 -167

passive smoking, 400

proposed agenda, 88

smoker compensation, 88

secondhand smoke. See Environmental tobacco smoke; Nonsmokers' rights; Passive smoking; Sidestream smoke

self-extinguishing cigarette. See Fire-safe cigarette

self-policing of industry, on additives, 230 -231

selling cigarettes, nicotine addiction, 97

selling doubt, 190

sexual activity, in rats exposed to cigarette smoke, 144

Sharkey's Machine, product placement in, 390

Ship, Project, attribution problem, 265 -266

Shook, Hardy, and Bacon

Addiction Research Foundation, 304 -305

additives testing, 230

Aviado, Domingo, 307 , 308 -310, 320 -321

concern about statements of industry scientists, 268 -271

glycoproteins, 397

Hickey, Richard, 331

Huber, Gary, 331 , 394

industry scientists attending scientific meetings, 319 -320

IT Corporation, 332

Kentucky Tobacco and Health Research Institute, 315 -316

Kronberg Research Conference, 132

passive smoking lawsuit, 251

Public Smoking Advisory Group, 394

Response Analysis Corporation study of environmental tobacco smoke, 311 -312

Rothschild, Henry, 291

Seltzer, Carl, 293 -295

Solomon, Lewis, 336

special account 4, 305 -306

Sterling, Theodor, 296 -301, 323 -325, 410 -411

tobacco substitutes, 162 -163

Washington University site visit, 311

Shook, Hardy, Ottman, Mitchell, and Bacon. See Shook, Hardy, and Bacon

short-term biological tests

carcinogenesis, correlation with, 153

ciliastatis, 151

commercial advantage, 153

difficulties interpreting, 133

hyperplasia, 152

mouse skin painting, correlation with, 153

"safe" cigarette, 151 -154

shredded dried stems, lowering of carbon monoxide yield, 168

sick building syndrome, and environmental tobacco smoke, 301 , 410 -411

sidestream smoke

Ames test of mutagenicity, 401

benzo(a)pyrene in, 402

biological activity of, 402

biological testing, avoidance of, 245

carbon monoxide in, 402

definition, 391 -392

development of less irritating smoke, 399

emissions, reduced, 405

factors controlling production of, 400

glycoproteins in, 432

irritation, 404

mainstream smoke, comparison with, 402

nitrosamines in, 400 , 402 , 403 -404, 432

product design, effect on, 410

reduced delivery cigarettes, 22

research objective, 433

self-extinguishing cigarette, 406

social aspects of, 404

toxicity of, 409

visibility of, 245 , 409


534

sidestream smoke (continued)

See also Environmental tobacco smoke; Nonsmokers' Rights; Passive smoking; Public smoking

smoke

Ames test, 229

arsenic, 31

cyanide, 154

insecticides, 31

Kent Golden Lights cigarettes, 154

L&M Flavor Lights cigarettes, 154

Liggett, 154

Lorillard, 154

Merit cigarettes, 154

nitrogen oxides, 154

Philip Morris, 154

R. J. Reynolds, 154

Real Menthol cigarettes, 154

smoke elasticity

filter design, 279 -280

Montreal Research Conference (1984), 90

smoke inhalability

anesthetic, effect of, 219

humectants, effect of, 211

sugar, effect of, 211

Smoke Ring, 347

smokeless tobacco, health benefits, inappropriate statements by US Tobacco, 274 -275

Smokeless Tobacco Council

description, 312

funding, 312

lawyers' role in, 312 -313

public relations device, 313 -314

response to Surgeon General's Advisory Committee on Health Consequences of Smokeless Tobacco, 313 -314

smoker compensation

Ames test results, 149 -150

Benowitz, Neal, 90

cigarette design, effect of, 141 , 142

definition, 87

elasticity, definition, 90

filter design, 280

human smoking patterns, 141

Kippa study, 87

legal aspects of, 88

low-nicotine cigarettes, 16 , 88

low-tar cigarettes, 16

marketing cigarettes, 375

mutagenicity, 142

nicotine

—absorption, 94

—delivery, 96 , 97

overview, 87 -91

physical sensations, 91

physician recommendations to smoke low-nicotine cigarettes, 90 -91

political aspects of, 88

regulatory aspects of, 89 , 91

smoke elasticity, 89

ventilation, effect of, 87

See also Nicotine delivery

smoker satisfaction, nicotine dose, 93

smoker's cough, as equalivent to bronchitis, 112

smokers' rights, 408 , 427

smokers' rights organizations, 252

smoking and disease, denial of relationship by industry officials, 156 -157

smoking-and-health controversy. See Creating controversy

smoking behavior

nicotine as determining factor, 96

Smoking Behavior Marketing conference, Montreal (1984), 374 -376

smoking machine, compared with, 142

smoking cessation, industry concern that Chase Bank in New York permitted a stop-smoking clinic on their premises, 355

smoking machine

Barclay cigarettes, 89

deMaurier Light King Size cigarettes, relationship between results of human and machine smoking, 150

human smoking, compared with, 142 , 150

Imperial Tobacco (Canada), 150

regulatory implications, 91

smoking patterns, mutagenicity, 142

smoking restrictions

cigarette sales, impact on, 426 -427

litigation to fight, 260

National Academy of Sciences, support of, 430

public support for, 425

tobacco advertising to counter, 188

Smoking and Health: A Report to the Surgeon General. See Surgeon General's Report, 1964

Smoking and Health Characteristics,323 -324

Snow White controversy

product placement, as making less attactive, 372

theater advertisements for Kool cigarettes, 363 -364, 387

snuff, as alternative to cigarettes in face of declining social acceptability, 84

social acceptability of smoking

antidote, 392

behavior of smokers, 408

defensive research, 139 , 407 -408

economic muscle to convince other companies to support industry position, 355 -356

emerging problem, 248 , 258

marketing issues, 339 , 401 -402

nonsmokers' rights initiatives, defeat of, 352

Roper Organization study for Tobacco Institute (1978), 392

sidestream smoke, 404

smoker behavior, effects on, 139

snuff, as alternative to cigarettes, 84

tobacco advertising, 188

tobacco industry, threat to, 84 , 248 , 392

workplace smoking restrictions, 250 -251, 409

source of Brown and Williamson documents. See Butts, Mr.

Southampton Research Conference (1984), low-sidestream-smoke cigarettes, 407 -410

Southampton technical exchange meeting on nicotine, 94 -97

Southern Association of State Departments of Agriculture, Tobacco Institute support of, 385

Souza Cruz (Brazil), BAT, 5

special account 4

administration by Jacob and Medinger, 305

administration by Jacob, Medinger, and Finnegan, 251

Aviado, Domingo, 307 -310

environmental tobacco smoke study, 306 -307

Fisher, H. Russell, 312 -313

Sterling, Theodor, 299 -300


535

special projects

Ad Hoc Committee, 290

Council for Tobacco Research, 240

definition, 289

evidence against independence of Council for Tobacco Research, 326 -327

government policy, influencing of, 323 -325

lawyers, awarding of, 46

money for, as coming from pooled contributions of companies according to market share, 290

recipients, 328 -338

secrecy of, 326 -327

start of, 1966, 290

Tobacco Industry Research Council, 240

university projects, 310 -311

See also Council for Tobacco Research

spectra. See N-Bloctin

Stanford Research Institute, special account 4 research project, 336

Star Chamber , product placement in, 390

State Governmental Affairs Council, Tobacco Institute support of, 386

State Legislative Leaders Foundation, Tobacco Institute support of, 386

State Mutual Life Assurance, study showing that smokers die younger than nonsmokers, negative for industry, 353

statistical association, versus causation, 341 , 342 -343

stress, and smoking, 62 -63

stroke, Surgeon General's report, 19

subpoena, for documents

Congress, 13 -14, 239

news organizations, 8 , 9

sucker control agents

biological tests of, 204

limited regulatory authority of US Department of Agriculture, 203

nicotine levels in leaf, effect on, 203

purpose, 203

Sucker Control Committee, 203

See also MH-30; Penar

Sucker Control Committee, membership, 203

sugar

additive, 211 , 218

inhalation, as making tobacco smoke easier to inhale, 211

Real cigarettes, 218

tobacco, 202

Summertime , product placement in, 390

Superdome decision, public relations benefits to industry, 353

Supergirl

Eve cigarettes, placement in, 368

Liggett and Myers products, placement in, 368

product placement solicitation, 367

Superman II , Marlboro product placement in, 367 , 372

Superman III , product placement opportunities, 367

Surgeon General, call for general need for understanding biological activity, 142

Surgeon General's Advisory Committee nicotine addiction versus habit, 100 -101

withholding information, as contrasted with Frank Statement , 74

withholding information on Avalon filter, 72 -73

withholding research on nicotine, 50 , 70 -73

See also Surgeon General's report, 1964

Surgeon General's Advisory Committee on Health Consequences of Smokeless Tobacco, 313 -314

Surgeon General's report

1964, xiii -xiv, 1 , 15 , 18 , 21 , 26 , 48 -49, 50 -54, 70 -73, 101 , 172 , 224 , 257 , 441

1966, 16

1972, 19 , 22

1973, 384

1979, 15 , 16

1981, 16 , 20

1982, 22

1983, 356

1986, 22 , 392

1989, 20

aortic aneurysm, 19

bladder cancer, 18 , 19

cardiovascular disease, 49

chronic bronchitis and emphysema, 18 , 49

coronary artery disease, 18

environmental tobacco smoke, 22

esophageal cancer, 19

fetal growth, 19

Health Effects of Involuntary Smoking (1986), 392

larynx cancer, 18

lip cancer, 19

Nicotine Addiction (1988), xiii -xiv, 15 , 58 , 87

oral cancer, 19

pancreatic cancer, 19

passive smoking, 384

peptic ulcer, 19

peripheral vascular disease, 19

pregnancy, 19

public relations, as negative development for industry, 352

reaction of industry, 50 -54

smokeless tobacco, 313 -314

Smoking and Health (1964), 1 , xiii -xiv

special account for consultancy to review 1979 report, 330

strategy for dealing with 1964 report, 52 -56

stroke, 19

tobacco industry efforts to influence media coverage, 356

tobacco price supports of export subsidiaries started after, 257

YouMaySmoke , attacked in, 174

Surgeon General's warning, used as defense against Federal Trade Commission, 261

Sydney Research Conference (1978), 139 -140, 398 -399

synthetic smoking material, criteria for use, 131

T

tar derby

cigarette advertising, impacts on, 27 -28, 259

Consumers Union, 28

contrast with later reluctance to imply health benefits, 274

response to cancer scare, 26 -28

tar wars, also called, 25 , 161

Tobacco Working Group, 161

tar market, 243

Tarrance & Associates, Proposition 5 pollster, 419 , 421 , 423

taste, relationship to nicotine, 104

taxation

discouragement of children from smoking, 249


536

taxation (continued)

nicotine content, taxation based on, 258 -259

Technical Advisory Group, for fire-safe cigarettes, 252

Ted Bates and Company, research on Barron's editorial, 178

television advertising ban

benefits to industry, 258

product placement in films as circumvention of, 365 , 368 -369, 374 -390

Tempest , product placement in, 368 -369, 371 , 373

Theatres West, Kool Jazz advertisements in, 387

Tiderock Corporation

American Medical Association, 181 , 184

Barron's editorial, 175 -178

True magazine article, 179 , 180

YouMaySmoke , 174

Time, Inc., meeting with high-level industry executives regarding Surgeon General's 1983 report, 356

TIRC. See Tobacco Industry Research Committee

titanium dioxide

additive, 227

filter, 227 , 228

TMSC. See Tobacco Manufacturers' Standing Committee

tobacco

high-nicotine, 85

nicotine content enriched in Ariel cigarettes, 75 -76

Tobacco Advisory Committee

annual pesticide residue meeting (in US), 209

Tobacco Research Council, previous name, 48

Tobacco Associates, site visit to Washington University, 311

tobacco blend

biological activity

—effect on, 152 -153

Vto reduce, 125

tobacco company projects, definition, 289

tobacco control program, 436

tobacco extract

additive, 85

Premier cigarettes, used in, 219

tobacco glycoproteins. See Glycoproteins

tobacco industry credibility, as low, 392 , 419

Tobacco Industry Research Committee

Battelle Memorial Institute research, 70

collaborative research among companies, 122

consistency of industry message over time, 342 , 343

Council for Tobacco Research, renamed, 32

formation and role, 17 , 32

founding members, 33

Frank Statement to Cigarette Smoker , 33 -35

Hill and Knowlton, 33 , 39 -40

independence, assurances of, 42

lawyers' role in, 36

organization and policy of, 33 -36

policy regarding publication of research, 321 -322

public relations role of, 26 , 33 , 39 -40, 53 , 358 -359

"safe" cigarette research, 53

Scientific Advisory Board, 35 , 42

special projects, 240

staff overlap with Tobacco Institute and Hill and Knowlton, 40

Surgeon General's 1964 report, planned reaction to, 50 -52

Tobacco Institute, staff overlap, 40

Tobacco Manufacturers' Standing Committee, contrast with, 47 -48

tobacco industry-sponsored symposia

ALEPH Foundation, 321

industry lawyers, use by, 351

Rylander symposium, 309

Sterling, Theodor, 300 , 321

Tobacco Institute

ACVA Atlantic Study, selection of homes for environmental tobacco smoke study, 411

additives, 211 , 223 , 225 , 226 , 227 -228, 231

advertisement based on Barron's editorial, 176 -177

American Legislative Exchange Council, support of, 385

American Society of Legislative Clerks and Secretaries, support of, 385

Amusement and Music Operators Association, support of, 386

Chemosol research, role in coordinating, 213 -216

Committee of Counsel, 156

Communications Committee, 193 -194

community organizations, donations to, 362

Council of State Governments, support of, 385

criticized for moving too slowly, 190

efforts to influence high-level media management regarding legislation, 356

environmental tobacco smoke, selection of homes for ACVA study of, 411

Executive Committee recruitment to contact high-level media executives, 326 -358

formation of, 39

Hill and Knowlton, staff overlap, 40

National Association of Attorneys General, support of, 385

National Association of Convenience Stores, support of, 386

National Association of Counties, support of, 385

National Association of Latino Elected Officials, support of, 385

National Association of Neighbors, support of, 386

National Association of State Departments of Agriculture, support of, 385

National Black Caucaus of State Legislators, support of, 385

National Cancer Institute study of additives, 227

National Center for Initiative Review, support of, 385

National Conference of State Legislatures, support of, 386

National League of Cities, support of, 386

National Legislative Services and Securities, support of, 386

National Licensed Beverage Association, support of, 386

National Order of Women Legislators, support of, 386


537

passive smoking and lung cancer, acceptance of consultants, 415

political organizations, contributions to, 385 -386

pressure on companies to not adopt anti-smoking positions, 355

Public Affairs Council, support of, 386

public relations, 254 -255, 40

Public Smoking Advisory Group, 394

Regional Governors' Associations, support of, 386

Roper Organization study for (1978), 392

Seltzer, Carl, trip to Australia sponsored by, 294

social acceptability of smoking and tobacco industry, 392

Southern Association of State Departments of Agriculture, support of, 385

staff overlap with Hill and Knowlton and TIRC, 40

State Governmental Affairs Council, support of, 386

State Legislative Leaders Foundation, support of, 386

state lobbying budget, 362 -363

Surgeon General's 1964 report, planned reaction to, 50 -52

timorous approach to smoking and health issues, 54

Tobacco Industry Research Committee, staff overlap, 40

Tobacco Working Group, reaction to draft press releases, 158

True magazine article, 179

US Council of Mayors, support of, 386

Washington University site visit, 311

Women Involved in Farm Economics, support of, 386

workplace smoking, opposition to restrictions on, 250 -251

tobacco leaf chemical composition, deadwood documents, 246

Tobacco Manufacturers' Standing Committee

cardiovascular effects of nicotine, 97 -98

Fisher, Sir Ronald A., 186

formation of, 47

Harrogate laboratory, 113

mouse skin-painting capacity of Harrogate laboratory, 114 -115

nicotine, beneficial effects of, 60 -61

Royal College of Physicians Report, reaction to, 47 , 111 -112

Tobacco Advisory Committee, name changed to, 48

Tobacco Industry Research Committee, comparison with, 47 -48

Tobacco Research Council, name changed to, 48

tobacco price supports, 257

Tobacco Research Council

Battelle Memorial Institute research, 70

carcinogenesis research, 137 -138

DDT residues, analysis of US imports for, 209

glycoproteins, 397

Janus, Project, relationship to, 144

Keogh, Dr., 198

mouse skin-painting experiments, 123

Penar, 204 -205, 206

smoking and lung cancer, 152

Tobacco Advisory Committee, name changed to, 48

Tobacco Manufacturers' Standing Committee, previously named, 48

YouMaySmoke , funding for, 174

Tobacco Securities Trust, 5

tobacco smoke condensate, fresh versus old, 116 -117

tobacco-specific N-nitrosamines (TSNA). See Nitrosamines

tobacco substitutes

Batflake, 164 -165

cytrel, 164

Hunter Commission, 163

Imperial Chemical Industries, 162 -163

marketing of cigarettes using, 166

National Cancer Institute, 163

overview, 162 -166

Philip Morris, 164

Planet cigarettes, 163

Reynolds, R. J., 164

toxicity, reduction, 126 , 137 -138

tobacco tar. See Mouse skin painting

tobacco tax. See Taxation

tobacco type, relationship to smoking patterns, 142

Tobacco Workers International Union, assistance in effort against California Proposition 5 , 419

Tobacco Working Group

industry influence on press statements, 157 -158

industry view of, 156

membership in, 155

National Cancer Institute, 155 -162

"safe" cigarette program rationale, 159 -160

scientific goals, 157

termination of, 161

Tso, T. C., 207

tolerance. See Nicotine addiction, tolerance

toxicity

different cigarette brands, 160 -161

MH-30, 203 , 204

pyrolysis, effect of, 211

trade secrets, regarding fire-safe cigarette, 253

tranquilizers

competitors to cigarettes, 344

nicotine

—comparison with, 62 , 73 , 75

—tranquilizing effect of, 64

Trans World Airlines, use of industry economic influence to affect company's policies on smoking, 355

True cigarettes

advertisement of, 16

smoking-and-health controversy for marketing purposes, 259

True magazine article, 179 -180

truth, and legal liability, 4

TSNA. See Nitrosamines

tumorgenicity

additives, 19

cigarette manufacturing process, effect on, 136 -137

potassium carbonate, 145

puff volume, effects on, 146

Two for the Price of One , product placement in, 390

U

UCLA, research funded by industry, 310 -311

UCSF library, housing Brown and Williamson documents, xix , 9


538

ulcer, peptic, Surgeon General's report, 19

underground trains, environmental tobacco smoke, 412 -413

unfair trade practices, concern about industry use of economic pressure to stop anti-smoking positions, 355

uninhalable cigarettes, as protection against emphysema, bronchitis, and cardiovascular disease, 130

Union Carbide, diethylene glycol, 224 -225

United Artist theaters, Kool Jazz advertisements in, 387

Universal Amusement, Kool Jazz advertisements, 387

university special projects, 310 -311

University of California

Brown and Williamson documents, xix , 9

lawsuit by Brown and Williamson against, 10 -11

"Up from the Bomb Shelter," 259 -263

US Council of Mayors, Tobacco Institute support of, 386

US Tobacco

Addiction Research Foundation, 304

health benefits, inappropriate statements regarding, 274 -275

Tobacco Industry Research Committee, 33

Washington University site visit, 311

USDA. See Department of Agriculture

V

Vantage cigarettes

advertisement of, 16

coumarin in, subsequently removed, 222

smoking-and-health controversy as advertising advantage, 259

vapor phase, not tested in mouse skin-painting experiments, 204

vascular disease, peripheral, Surgeon General's report, 19

ventilation

Council for Tobacco Research special project, 333

environmental tobacco smoke, 22

mutagenicity, increased, 149

smoker compensation, 87

Verband (German)

nitrosamines, 143

passive smoking and lung cancer, 415

Viceroy cigarettes

advertising claims of, 28 , 29

advertising to communicate health and political information, 191

bad publicity regarding advertising memorandum, 372

cellulose filters, 29

health guard filter, 29

Hilton, Project, to test, 153

hyperplasia test, 153

inhalation testing, 153

Vienna Symposium, use by industry lawyers to exonerate environmental tobacco smoke, 351

visibility. See Sidestream smoke, visibility

vitamin A, as anticancer additive in tobacco, 147

W

Wacko , product placement, 390

Wall Street Journal , exposing True magazine article, 179

warning labels

defense against

—Federal Trade Commission, 261

—liability, 54 , 255 -256, 342

difference in legal situations when warning labels are and are not required, 342

nicotine addiction warning, avoidance of, 59 -60

requirement on cigarette packages, 175

Sterling, Theodor, 300

Washington University

other special project, 337

public relations plus for industry, 353

tobacco industry, funding of research by, 310 -311

water conditioners, residues in tobacco, 202

weight, effect of nicotine on, 69

Wheat, Project, purpose, 92

Winchester, R. J. Reynolds little cigar, 259

Winston cigarettes

Never Say Never Again , appearance in, 371

problems created by less toxic cigarettes, 440

withdrawal. See Nicotine, withdrawal

withholding information, from Surgeon General's Advisory Committee, 70 -73

Women Involved in Farm Economics, Tobacco Institute support of, 386

Woodward & McDowell

management of No-on-5 campaign, 420 -421

proposal to attack legislature, 424 -425

work product rule

avoidance of discovery, 241

Brown and Williamson documents, 236

explanation, 237 -238

fraud exception, 237 -238

prevention of documents from being made public, 3

workplace smoking

American Tobacco did not want to study, 251

avoiding adverse effects on sales, 409

Battelle Memorial Institute, 251

impact on tobacco sales, 426 -427

importance to industry, 393

industry claims of costs, 422

industry studies of, 251

litigation on, 251

Lorillard wanted to study, 251

lung function, effects on, 428 -429

model ordinance produced by industry, 251

New Jersey, proposed smoking restriction, 431

Occupational Safety and Health Administration, 436

Philip Morris did not want to study, 251

Proposition 5 , 417 -428

Proposition 10 , 352 , 428 -431

Proposition P, 431

public support for restrictions on, 425 , 430 -431

R. J. Reynolds did not want to study, 251

Sterling, Theodor, creation of controversy regarding passive smoking, 411

World College of Physicians Report, Sir Charles Ellis's reaction to, 60 -61

World Conference on Smoking and Health

Fifth, 309

Fourth, 352

World War I, 217

World Wide Web, Brown and Williamson documents on, 3 , 11


539

Wyatt, Tarrant, and Combs, document review project, 7 , 15 -16, 249

Y

yeast system, as bioassay, 149

YouMaySmoke , 174 -175

young starters. See Children

Z

zealots, 393

ZEPHYR, as code name for lung cancer, 109 -110, 132 . See also Lung cancer

zoo animals, Council for Tobacco Research special projects, 334


540

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